Gurnee Carolyn M, Drobatz Kenneth J
Matthew J. Ryan Veterinary Hospital, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-5438, USA.
J Am Vet Med Assoc. 2007 Apr 15;230(8):1174-9. doi: 10.2460/javma.230.8.1174.
To determine physical examination findings, clinicopathologic changes, and prognosis in dogs with zinc toxicosis.
Retrospective case series.
19 dogs with zinc toxicosis.
Medical records from 1991 through 2003 were searched for animals with a diagnosis of zinc toxicosis. Information concerning signalment, body weight, historical findings, initial owner complaints, physical examination findings, clinicopathologic findings, blood zinc concentrations, source of zinc, treatments given, duration of hospital stay, and outcome was collected.
Records of 19 dogs with zinc toxicosis were reviewed. The most common historical findings were vomiting (n = 14) and pigmenturia (12). The most common clinicopathologic findings were anemia (n = 19) and hyperbilirubinemia (12). Median age was 1.3 years, and median weight was 5.6 kg (12.3 lb). The prognosis was favorable, with 17 dogs surviving after a median hospital stay of 2 days.
Hemolytic anemia as a result of zinc toxicosis appeared to affect young small-breed dogs more frequently than older large-breed dogs. The prognosis with treatment is good, and most affected dogs had a short hospital stay.
确定锌中毒犬的体格检查结果、临床病理变化及预后情况。
回顾性病例系列研究。
19只锌中毒犬。
检索1991年至2003年的病历，查找诊断为锌中毒的动物。收集有关动物特征、体重、既往病史、主人最初的主诉、体格检查结果、临床病理检查结果、血锌浓度、锌来源、给予的治疗、住院时间及转归等信息。
对19只锌中毒犬的病历进行了回顾。最常见的既往病史为呕吐（n = 14）和血红蛋白尿（12例）。最常见的临床病理检查结果为贫血（n = 19）和高胆红素血症（12例）。中位年龄为1.3岁，中位体重为5.6 kg（12.3磅）。预后良好，17只犬在中位住院2天后存活。
锌中毒所致溶血性贫血似乎在年轻小型犬中比老年大型犬中更常见。经治疗预后良好，大多数患病犬住院时间较短。
