1991年海湾战争澳大利亚退伍军人的生殖健康

Reproductive health of male Australian veterans of the 1991 Gulf War.

作者信息

Kelsall Helen L, Sim Malcolm R, Ikin Jillian F, Forbes Andrew B, McKenzie Dean P, Glass Deborah C, Ittak Peter

机构信息

Department of Epidemiology and Preventive Medicine, Monash University--Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria, Australia.

出版信息

BMC Public Health. 2007 May 16;7:79. doi: 10.1186/1471-2458-7-79.

DOI:10.1186/1471-2458-7-79

PMID:17504542

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1885426/

Abstract

BACKGROUND

Since the 1991 Gulf War concerns have been raised about the effects of deployment to the Gulf War on veterans' health. Studies of the reproductive health of Gulf War veterans have reported varied findings.

METHODS

We undertook a cross-sectional study of male Australian Gulf War veterans (n = 1,424) and a randomly sampled military comparison group (n = 1,548). The study was conducted from August 2000 to April 2002. A postal questionnaire included questions about difficulties achieving pregnancy, pregnancy outcomes including live births, stillbirths, miscarriages and terminations; and for all live births gestation, birth weight, sex, and any cancers, birth defects, chromosomal abnormalities or serious health problems.

RESULTS

Male Gulf War veterans reported slightly increased risk of fertility difficulties following the Gulf War (odds ratio [OR] 1.4; 95% confidence interval [CI] 1.0-1.8), but were more successful at subsequently fathering a child (OR 1.8; 95% CI 1.3-2.6). The study groups reported similar rates of pregnancies and live births. There was no increased risk in veterans of miscarriage, stillbirth, or terminations. Children of male Gulf War veterans born after the period of the Gulf War were not at greater risk of being born prematurely, having a low birth weight, or having a birth defect or chromosomal abnormality (OR 1.0; 95% CI 0.6-1.6). The numbers of cancers and deaths in children were too small to draw any firm conclusions.

CONCLUSION

The results of this study do not show an increased risk of adverse reproductive outcome in Australian male Gulf War veterans.

摘要

背景

自1991年海湾战争以来，人们一直对海湾战争部署对退伍军人健康的影响表示担忧。关于海湾战争退伍军人生殖健康的研究报告了各种各样的结果。

方法

我们对1424名澳大利亚男性海湾战争退伍军人和一个随机抽样的军事对照组（1548人）进行了一项横断面研究。该研究于2000年8月至2002年4月进行。一份邮寄问卷包括关于受孕困难的问题、妊娠结局，包括活产、死产、流产和终止妊娠；以及所有活产的孕周、出生体重、性别，以及任何癌症、出生缺陷、染色体异常或严重健康问题。

结果

男性海湾战争退伍军人报告称，海湾战争后生育困难的风险略有增加（优势比[OR]为1.4；95%置信区间[CI]为1.0 - 1.8），但随后生育孩子的成功率更高（OR为1.8；95% CI为1.3 - 2.6）。研究组报告的怀孕和活产率相似。退伍军人流产、死产或终止妊娠的风险没有增加。海湾战争期间之后出生的男性海湾战争退伍军人的子女早产、低出生体重、出生缺陷或染色体异常的风险没有增加（OR为1.0；95% CI为0.6 - 1.6）。儿童癌症和死亡的数量太少，无法得出任何确凿结论。