Suppr超能文献

1991年海湾战争澳大利亚退伍军人的症状与医疗状况:与免疫接种及其他海湾战争接触因素的关系

Symptoms and medical conditions in Australian veterans of the 1991 Gulf War: relation to immunisations and other Gulf War exposures.

作者信息

Kelsall H L, Sim M R, Forbes A B, Glass D C, McKenzie D P, Ikin J F, Abramson M J, Blizzard L, Ittak P

机构信息

Department of Epidemiology and Preventive Medicine, Monash University-Central and Eastern Clinical School, Alfred Hospital, Commercial Road, Melbourne, Victoria, Australia.

出版信息

Occup Environ Med. 2004 Dec;61(12):1006-13. doi: 10.1136/oem.2003.009258.

Abstract

AIMS

To investigate whether Australian Gulf War veterans have a higher than expected prevalence of recent symptoms and medical conditions that were first diagnosed in the period following the 1991 Gulf War; and if so, whether these effects were associated with exposures and experiences that occurred in the Gulf War.

METHODS

Cross-sectional study of 1456 Australian Gulf War veterans and a comparison group who were in operational units at the time of the Gulf War, but were not deployed to that conflict (n = 1588). A postal questionnaire was administered and the likelihood of the diagnosis of self-reported medical conditions was assessed and rated by a medical practitioner.

RESULTS

Gulf War veterans had a higher prevalence of all self-reported health symptoms than the comparison group, and more of the Gulf War veterans had severe symptoms. Increased symptom reporting was associated with several exposures, including having more than 10 immunisations, pyridostigmine bromide tablets, anti-biological warfare tablets, pesticides, insect repellents, reportedly being in a chemical weapons area, and stressful military service experiences in a strong dose-response relation. Gulf War veterans reported psychological (particularly post-traumatic stress disorder), skin, eye, and sinus conditions first diagnosed in 1991 or later more commonly than the comparison group. Over 90% of medical conditions reported by both study groups were rated by a medical practitioner as having a high likelihood of diagnosis.

CONCLUSION

More than 10 years after the 1991 Gulf War, Australian veterans self-report all symptoms and some medical conditions more commonly than the comparison group. Further analysis of the severity of symptoms and likelihood of the diagnosis of medical conditions suggested that these findings are not due to over-reporting or to participation bias.

摘要

目的

调查澳大利亚海湾战争退伍军人近期首次诊断出的症状和疾病患病率是否高于预期,这些症状和疾病首次出现在1991年海湾战争之后;如果是这样,这些影响是否与海湾战争期间的接触和经历有关。

方法

对1456名澳大利亚海湾战争退伍军人以及一个对照组进行横断面研究,对照组是在海湾战争期间在作战部队但未被部署到该冲突地区的人员(n = 1588)。通过邮寄问卷进行调查,并由一名医生评估和评定自我报告的疾病诊断可能性。

结果

海湾战争退伍军人自我报告的所有健康症状患病率均高于对照组,且更多海湾战争退伍军人有严重症状。症状报告增加与多种接触有关,包括接种超过10次疫苗、服用溴吡斯的明片、服用防生物战药片、接触杀虫剂、驱虫剂、据报道身处化学武器区域以及高强度应激的军事服役经历,呈现出强剂量反应关系。海湾战争退伍军人报告的心理(尤其是创伤后应激障碍)、皮肤、眼睛和鼻窦疾病首次诊断于1991年或之后的情况比对照组更为常见。两个研究组报告的疾病中,超过90%被医生评定为诊断可能性高。

结论

在1991年海湾战争过去10多年后,澳大利亚退伍军人自我报告的所有症状和一些疾病比对照组更为常见。对症状严重程度和疾病诊断可能性的进一步分析表明,这些发现并非由于报告过度或参与偏倚所致。

相似文献

4
Health consequences of the first Persian Gulf War on French troops.第一次海湾战争对法国军队的健康影响。
Int J Epidemiol. 2006 Apr;35(2):479-87. doi: 10.1093/ije/dyi318. Epub 2006 Jan 24.
9
[The Gulf War Syndrome twenty years on].二十年后的海湾战争综合征
Encephale. 2013 Oct;39(5):332-8. doi: 10.1016/j.encep.2012.11.003. Epub 2013 Jan 23.

引用本文的文献

3
Cytotoxic Effects of -Diethyl--Toluamide (DEET) on Sinonasal Epithelia.避蚊胺(DEET)对鼻窦上皮细胞的细胞毒性作用。
OTO Open. 2021 May 4;5(2):2473974X211009232. doi: 10.1177/2473974X211009232. eCollection 2021 Apr-Jun.
4
Multiple Vaccinations and the Enigma of Vaccine Injury.多种疫苗接种与疫苗伤害之谜
Vaccines (Basel). 2020 Nov 12;8(4):676. doi: 10.3390/vaccines8040676.

本文引用的文献

5
Kappa coefficients in medical research.医学研究中的卡帕系数。
Stat Med. 2002 Jul 30;21(14):2109-29. doi: 10.1002/sim.1180.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验