Jayjock Michael A, Chaisson Christine F, Arnold Susan, Dederick Elizabeth J
The LifeLine Group, Langhorne, Pennsylvania 19047, USA.
J Expo Sci Environ Epidemiol. 2007 Dec;17 Suppl 1:S81-9. doi: 10.1038/sj.jes.7500580. Epub 2007 May 16.
We are at the dawn of a new era of quantitative consumer exposure and risk assessment of chemicals driven by regulatory mandates. This remarkable development also signals the beginning of a dramatic resurgence in the need for and development of human exposure models. This paper presents some of the philosophical background underlying exposure modeling in the context of human health risk assessment. The basic types of and structure of inhalation exposure models are discussed, as well as the research needed to move us forward into this exciting new period of development.
在监管要求的推动下，我们正处于化学物质定量消费者接触和风险评估新时代的开端。这一显著发展也标志着对人类接触模型的需求和开发急剧复苏的开始。本文介绍了人类健康风险评估背景下接触建模的一些哲学基础。讨论了吸入接触模型的基本类型和结构，以及推动我们进入这一令人兴奋的新发展时期所需的研究。
