Kempley S T, Gamsu H R, Vyas S, Nicolaides K
King's College Hospital, London.
Arch Dis Child. 1991 Oct;66(10 Spec No):1115-8. doi: 10.1136/adc.66.10_spec_no.1115.
Blood flow velocity and pulsatility index were measured with Doppler ultrasound in the superior mesenteric artery, coeliac axis, and anterior cerebral artery in 18 very low birth weight, small for gestational age infants, and compared with findings from 18 weight matched, and 18 gestation matched, appropriate for gestational age controls. Mean velocity in the superior mesenteric artery was lower in the small for gestational age infants (15 cm/s) than in the gestation matched control group (20.4 cm/s). In those small for gestational age infants who had evidence of fetal hypoxia the mean velocity in the superior mesenteric artery was even lower (11.5 cm/s). There were no differences in velocity in the cerebral artery among the groups. Infants who were small for gestational age still had significantly lower superior mesenteric artery velocity than gestation matched controls at 1 week of age. The results suggest a specific reduction in visceral perfusion in infants who are small for gestational age and who have experienced fetal hypoxia, and this could predispose these infants to necrotising enterocolitis.
采用多普勒超声测量了18例极低出生体重、小于胎龄儿的肠系膜上动脉、腹腔干和大脑前动脉的血流速度及搏动指数，并与18例体重匹配和18例孕周匹配的适于胎龄儿对照组的结果进行了比较。小于胎龄儿肠系膜上动脉的平均血流速度（15厘米/秒）低于孕周匹配的对照组（20.4厘米/秒）。在那些有胎儿缺氧证据的小于胎龄儿中，肠系膜上动脉的平均血流速度更低（11.5厘米/秒）。各组间脑动脉血流速度无差异。小于胎龄儿在1周龄时肠系膜上动脉血流速度仍显著低于孕周匹配的对照组。结果表明，小于胎龄且经历过胎儿缺氧的婴儿内脏灌注存在特异性降低，这可能使这些婴儿易患坏死性小肠结肠炎。
