喂食间隔和饲料类型对内脏血流动力学的影响。
Effect of feed interval and feed type on splanchnic haemodynamics.
作者信息
Lane A J, Coombs R C, Evans D H, Levin R J
机构信息
Department of Neonatology, Jessop Hospital for Women, Sheffield.
出版信息
Arch Dis Child Fetal Neonatal Ed. 1998 Jul;79(1):F49-53. doi: 10.1136/fn.79.1.f49.
Abstract
AIM
To study the effect of enteral feeding on splanchnic blood flow velocity in preterm infants.
METHOD
Coeliac axis and superior mesenteric artery (SMA) blood flow velocity were measured longitudinally in a cohort of 61 babies using Doppler ultrasound.
RESULTS
Babies fed 1 hourly had significantly higher preprandial SMA peak systolic velocity (PSV) than those fed 3 hourly (70 vs 53 cm/s). Those fed 1 hourly showed no postprandial change whereas those fed 3 hourly showed significant postprandial hyperaemia. This hyperaemia had longer latency (42 vs 27 mins) and smaller amplitude (31 vs 25 mins) after expressed breast milk compared with preterm formula. The addition of long chain polyunsaturated fatty acids to the formulas had no effect on the postprandial response.
CONCLUSION
Hourly bolus feeding leads to a persistent hyperaemic state in the SMA. The composition of feeds is an important determinant of the postprandial response of the SMA to 3 hourly feeding.
摘要
目的
研究肠内喂养对早产儿内脏血流速度的影响。
方法
采用多普勒超声纵向测量61例婴儿的腹腔干和肠系膜上动脉（SMA）血流速度。
结果
每小时喂养一次的婴儿餐前SMA峰值收缩速度（PSV）显著高于每三小时喂养一次的婴儿（70 vs 53 cm/s）。每小时喂养一次的婴儿餐后无变化，而每三小时喂养一次的婴儿餐后出现明显充血。与早产配方奶相比，母乳喂养后这种充血的潜伏期更长（42 vs 27分钟），幅度更小（31 vs 25分钟）。在配方奶中添加长链多不饱和脂肪酸对餐后反应无影响。
结论
每小时推注喂养会导致SMA持续充血状态。喂养的成分是SMA对每三小时喂养的餐后反应的重要决定因素。
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