围产期缺氧后基底神经节的短暂性高代谢。
Transient hypermetabolism of the basal ganglia following perinatal hypoxia.
作者信息
Batista Carlos E A, Chugani Harry T, Juhász Csaba, Behen Michael E, Shankaran Seetha
机构信息
Carman and Ann Adams, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan 48201, USA.
出版信息
Pediatr Neurol. 2007 May;36(5):330-3. doi: 10.1016/j.pediatrneurol.2007.01.004.
Positron emission tomography can be used to evaluate brain function following perinatal hypoxia. This case report demonstrates transient hypermetabolism in the basal ganglia detected by glucose metabolism positron emission tomography study in a newborn who suffered hypoxic-ischemic encephalopathy and developed dystonic cerebral palsy later. A scan repeated at 4 years of age showed severe hypometabolism in the lentiform nuclei and thalami. Transient hypermetabolism in the basal ganglia following perinatal hypoxia may be related to excitotoxic damage causing permanent neurological symptoms in the form of dystonic cerebral palsy. Thus, positron emission tomography can help predict this form of cerebral palsy in neonates.
正电子发射断层扫描可用于评估围产期缺氧后的脑功能。本病例报告显示，在一名患有缺氧缺血性脑病并随后发展为张力障碍型脑瘫的新生儿中，通过葡萄糖代谢正电子发射断层扫描研究检测到基底神经节出现短暂性高代谢。4岁时重复进行的扫描显示豆状核和丘脑严重代谢减退。围产期缺氧后基底神经节的短暂性高代谢可能与兴奋性毒性损伤有关，这种损伤会导致以张力障碍型脑瘫形式出现的永久性神经症状。因此，正电子发射断层扫描有助于预测新生儿的这种脑瘫形式。
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