粪碗菌中的抗氧化剂——粪碗菌素A、B和C，来自发酵后的粪碗菌（Cyathus stercoreus）。
Cyathusals A, B, and C, antioxidants from the fermented mushroom Cyathus stercoreus.
作者信息
Kang Hahk-Soo, Jun Eun-Mi, Park Soon-Hye, Heo Soo-Jin, Lee Tae-Soo, Yoo Ick-Dong, Kim Jong-Pyung
机构信息
KRIBB, 52 Eoeun-dong, Yuseong, Daejeon 305-806, Korea.
出版信息
J Nat Prod. 2007 Jun;70(6):1043-5. doi: 10.1021/np060637h. Epub 2007 May 19.
Three new polyketide-type antioxidative compounds, cyathusals A (1), B (2), and C (3), and the known pulvinatal (4) were obtained from the fermented mushroom Cyathus stercoreus. The structures of the compounds were characterized on the basis of NMR and mass spectroscopic data. Cyathusals A, B, and C and pulvinatal showed free radical scavenging activities on the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical with EC50 values of 41.6, 46.0, 26.6, and 28.6 microM, respectively, and on the 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) cation radical with EC50 values of 7.9, 11.1, 9.1, and 8.4 microM, respectively.
从发酵的粪生黑蛋巢菌（Cyathus stercoreus）中获得了三种新的聚酮类抗氧化化合物，即鸟巢菌素A（1）、B（2）和C（3），以及已知的普尔维纳托尔（4）。根据核磁共振（NMR）和质谱数据对这些化合物的结构进行了表征。鸟巢菌素A、B和C以及普尔维纳托尔对2,2-二苯基-1-苦基肼基（DPPH）自由基均表现出自由基清除活性，其半数有效浓度（EC50）值分别为41.6、46.0、26.6和28.6微摩尔/升，对2,2'-偶氮双（3-乙基苯并噻唑啉-6-磺酸盐）（ABTS）阳离子自由基的EC50值分别为7.9、11.1、9.1和8.4微摩尔/升。
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