Rosemann T, Szecsenyi J
University Hospital of Heidelberg, Department of General Practice and Health Services Research, Vosstrasse 2, 69115 Heidelberg, Germany.
Osteoarthritis Cartilage. 2007 Oct;15(10):1128-33. doi: 10.1016/j.joca.2007.03.021. Epub 2007 May 23.
To validate a translated and culturally adapted version of the Arthritis Impact Measurement Scale (AIMS) 2 in primary care patients with osteoarthritis (OA) of the hip and knee.
The AIMS2 was translated into German and culturally adapted. The questionnaire then was administered to 220 primary care patients with OA of the knee or hip. Two hundred and nine questionnaires were returned and analysed. Test-retest reliability was tested in 50 randomly selected patients, of those 42 completed the questionnaire after 2 weeks for a second time.
Item-scale correlations were reasonably good as well as the discriminative power of separate scales. The assessment of internal consistency reliability also revealed satisfactory values; Cronbach's alpha was 0.77 or higher for all scales. The test-retest reliability, estimated in an intraclass correlation coefficient (ICC), exceeded 0.90, except the "social activities" scale (0.87). Since only patients with OA of the lower limb were enrolled, substantial floor effects occurred in the "arm function" (28.2%) and the "hand and finger function" scale (29.2%). The principal factor analysis confirmed the postulated three-factor structure with a physical, physiological and social dimension, explaining 48.5%, 13.9% and 6.8% of the variation, respectively. External validity was assessed by calculating correlations to the Western Ontario and MacMaster (WOMAC) osteoarthritis questionnaire a pain visual analogue scale (VAS) and the Kellgren score as well as to disease duration. Spearman's "R" achieved satisfactory values for the corresponding WOMAC scales and the pain-VAS. Correlations with disease duration as well as with the radiological grading were low.
The GERMAN-AIMS2 is a reliable and valid instrument to assess the quality of life (QoL) in primary care patients suffering from OA.
验证关节炎影响测量量表（AIMS）2经翻译和文化调适后的版本在基层医疗中髋膝关节骨关节炎（OA）患者中的有效性。
将AIMS2翻译成德语并进行文化调适。然后对220例基层医疗中膝或髋OA患者进行问卷调查。共收回209份问卷并进行分析。在50例随机选择的患者中测试重测信度，其中42例在2周后再次完成问卷。
各条目与量表的相关性良好，各单独量表的区分能力也较好。内部一致性信度评估也显示出令人满意的值；所有量表的Cronbach's α系数均为0.77或更高。以组内相关系数（ICC）估计的重测信度，除“社会活动”量表（0.87）外，均超过0.90。由于仅纳入下肢OA患者，“手臂功能”量表（28.2%）和“手与手指功能”量表（29.2%）出现了显著的地板效应。主成分分析证实了假定的具有身体、生理和社会维度的三因素结构，分别解释了48.5%、13.9%和6.8%的变异。通过计算与西安大略和麦克马斯特大学（WOMAC）骨关节炎问卷、疼痛视觉模拟量表（VAS）、凯尔格伦评分以及疾病持续时间的相关性来评估外部效度。Spearman's “R”在相应的WOMAC量表和疼痛VAS上取得了令人满意的值。与疾病持续时间以及放射学分级的相关性较低。
德国版AIMS2是评估基层医疗中OA患者生活质量（QoL）的可靠且有效的工具。
