Donovan Kristine A, Jacobsen Paul B
Health Outcomes and Behavior Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
Semin Oncol Nurs. 2007 May;23(2):127-35. doi: 10.1016/j.soncn.2007.01.004.
To review the evidence for considering fatigue, depression, and insomnia as a symptom cluster in cancer.
Empirical studies, clinical articles, and review articles.
The single- and multi-symptom measurement approaches are of limited usefulness in distinguishing fatigue, depression, and insomnia. Studies in which these symptoms have been measured concurrently in patients with cancer yield consistent evidence of high positive correlations. Results do not appear to be solely a function of overlap in measurement approaches.
Successful management of fatigue, depression, and insomnia in cancer patients are likely to combine pharmacologic and nonpharmacologic therapies.
回顾将疲劳、抑郁和失眠视为癌症症状群的证据。
实证研究、临床文章和综述文章。
单症状和多症状测量方法在区分疲劳、抑郁和失眠方面作用有限。在癌症患者中同时测量这些症状的研究得出了高度正相关的一致证据。结果似乎并非仅仅是测量方法重叠的作用。
成功管理癌症患者的疲劳、抑郁和失眠可能需要结合药物和非药物治疗。
