胎盘催乳素是一种造血激素。

Placental lactogen is a haemopoietic hormone.

作者信息

Berczi I, Nagy E

机构信息

Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Br J Haematol. 1991 Nov;79(3):355-8. doi: 10.1111/j.1365-2141.1991.tb08040.x.

DOI:10.1111/j.1365-2141.1991.tb08040.x

PMID:1751362

Abstract

The anaemia and thrombocytopenia of hypophysectomized (Hypox) rats could be corrected readily by daily treatment with human placental lactogen. Spontaneous DNA synthesis in the bone marrow of Hypox rats was grossly impaired, which was also normalized by placental lactogen. Human placental lactogen exerted a direct mitogenic effect on rat bone marrow cells in vitro. These results indicate that placental lactogen is a potent haemopoietic hormone.

摘要

垂体切除（Hypox）大鼠的贫血和血小板减少症可通过每日用人胎盘催乳素治疗而轻易得到纠正。Hypox大鼠骨髓中的自发DNA合成严重受损，而胎盘催乳素也使其恢复正常。人胎盘催乳素在体外对大鼠骨髓细胞具有直接的促有丝分裂作用。这些结果表明，胎盘催乳素是一种有效的造血激素。