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胎盘催乳素是一种造血激素。

Placental lactogen is a haemopoietic hormone.

作者信息

Berczi I, Nagy E

机构信息

Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Br J Haematol. 1991 Nov;79(3):355-8. doi: 10.1111/j.1365-2141.1991.tb08040.x.

DOI:10.1111/j.1365-2141.1991.tb08040.x
PMID:1751362
Abstract

The anaemia and thrombocytopenia of hypophysectomized (Hypox) rats could be corrected readily by daily treatment with human placental lactogen. Spontaneous DNA synthesis in the bone marrow of Hypox rats was grossly impaired, which was also normalized by placental lactogen. Human placental lactogen exerted a direct mitogenic effect on rat bone marrow cells in vitro. These results indicate that placental lactogen is a potent haemopoietic hormone.

摘要

垂体切除(Hypox)大鼠的贫血和血小板减少症可通过每日用人胎盘催乳素治疗而轻易得到纠正。Hypox大鼠骨髓中的自发DNA合成严重受损,而胎盘催乳素也使其恢复正常。人胎盘催乳素在体外对大鼠骨髓细胞具有直接的促有丝分裂作用。这些结果表明,胎盘催乳素是一种有效的造血激素。

相似文献

1
Placental lactogen is a haemopoietic hormone.胎盘催乳素是一种造血激素。
Br J Haematol. 1991 Nov;79(3):355-8. doi: 10.1111/j.1365-2141.1991.tb08040.x.
2
Hypophysectomized rats depend on residual prolactin for survival.垂体切除的大鼠依靠残余的催乳素来维持生存。
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Effects of bovine growth hormone, human placental lactogen and ovine prolactin on intestinal fluid and ion transport in the rat.
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Ovine placental lactogen induces somatomedin: a a possible role in fetal growth.绵羊胎盘催乳素诱导生长调节素:对胎儿生长可能起的作用。
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Regulation of immunity in rats by lactogenic and growth hormones.催乳素和生长激素对大鼠免疫的调节
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Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy.同源胎盘催乳素、催乳素和生长激素对大鼠、小鼠及人胰岛B细胞分裂和胰岛素分泌的影响:对孕期胎盘催乳素调节胰岛功能的意义。
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Pituitary dependence of bone marrow function.骨髓功能对垂体的依赖性。
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Reactivation of regressing corpora lutea by estradiol in the pregnant rat: dependence on placental lactogen.孕鼠体内退化黄体经雌二醇重新激活:对胎盘催乳素的依赖性。
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引用本文的文献

1
The role of prolactin in the pathogenesis of autoimmune disease.催乳素在自身免疫性疾病发病机制中的作用。
Endocr Pathol. 1993 Dec;4(4):178-195. doi: 10.1007/BF02915460.