骨髓功能对垂体的依赖性。
Pituitary dependence of bone marrow function.
作者信息
Nagy E, Berczi I
机构信息
Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.
出版信息
Br J Haematol. 1989 Apr;71(4):457-62. doi: 10.1111/j.1365-2141.1989.tb06302.x.
Abstract
The anaemia, leucopenia, thrombocytopenia and impaired DNA and RNA synthesis in the bone marrow of hypophysectomized rats could be restored by syngeneic pituitary grafts placed under the kidney capsule, or by treatments with ovine or bovine prolactin or growth hormone. Treatment with ACTH, FSH, LH and TSH had no effect in this respect. These results indicate that bone marrow function is regulated by the pituitary gland.
摘要
垂体切除大鼠骨髓中的贫血、白细胞减少、血小板减少以及DNA和RNA合成受损，可通过置于肾被膜下的同基因垂体移植，或通过用羊或牛催乳素或生长激素治疗来恢复。在这方面，用促肾上腺皮质激素、促卵泡激素、促黄体生成素和促甲状腺激素治疗没有效果。这些结果表明骨髓功能受垂体调节。
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