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骨髓功能对垂体的依赖性。

Pituitary dependence of bone marrow function.

作者信息

Nagy E, Berczi I

机构信息

Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Br J Haematol. 1989 Apr;71(4):457-62. doi: 10.1111/j.1365-2141.1989.tb06302.x.

DOI:10.1111/j.1365-2141.1989.tb06302.x
PMID:2469458
Abstract

The anaemia, leucopenia, thrombocytopenia and impaired DNA and RNA synthesis in the bone marrow of hypophysectomized rats could be restored by syngeneic pituitary grafts placed under the kidney capsule, or by treatments with ovine or bovine prolactin or growth hormone. Treatment with ACTH, FSH, LH and TSH had no effect in this respect. These results indicate that bone marrow function is regulated by the pituitary gland.

摘要

垂体切除大鼠骨髓中的贫血、白细胞减少、血小板减少以及DNA和RNA合成受损，可通过置于肾被膜下的同基因垂体移植，或通过用羊或牛催乳素或生长激素治疗来恢复。在这方面，用促肾上腺皮质激素、促卵泡激素、促黄体生成素和促甲状腺激素治疗没有效果。这些结果表明骨髓功能受垂体调节。

相似文献

1
Pituitary dependence of bone marrow function.骨髓功能对垂体的依赖性。
Br J Haematol. 1989 Apr;71(4):457-62. doi: 10.1111/j.1365-2141.1989.tb06302.x.
2
Hypophysectomized rats depend on residual prolactin for survival.垂体切除的大鼠依靠残余的催乳素来维持生存。
Endocrinology. 1991 Jun;128(6):2776-84. doi: 10.1210/endo-128-6-2776.
3
Regulation of humoral immunity in rats by pituitary hormones.垂体激素对大鼠体液免疫的调节
Acta Endocrinol (Copenh). 1981 Dec;98(4):506-13. doi: 10.1530/acta.0.0980506.
4
Prolactin and contact sensitivity.催乳素与接触敏感性。
Allergy. 1981 Aug;36(6):429-31. doi: 10.1111/j.1398-9995.1981.tb01850.x.
5
Relation of gonadotropin secretion by pituitary grafts to spermatogenesis in hypophysectomized rats.垂体移植分泌的促性腺激素与去垂体大鼠精子发生的关系。
Endocrinology. 1977 Feb;100(2):380-6. doi: 10.1210/endo-100-2-380.
6
[Effect of pituitary growth hormone on granulopoiesis in the bone marrow of intact and hypophysectomized rats].[垂体生长激素对完整及垂体切除大鼠骨髓粒细胞生成的影响]
Probl Endokrinol (Mosk). 1972 May-Jun;18(3):100-4.
7
Placental lactogen is a haemopoietic hormone.胎盘催乳素是一种造血激素。
Br J Haematol. 1991 Nov;79(3):355-8. doi: 10.1111/j.1365-2141.1991.tb08040.x.
8
Experimental studies on hormonal regulation of heme synthesis in bone marrow. 3. Heme synthesis in bone marrow of Wistar rats deprived of the endocrine glands simultaneously and the effects of their hormones and pituitary hormones upon the decreased heme synthesis in hypophysectomized rats.骨髓中血红素合成的激素调节实验研究。3. 同时摘除内分泌腺的Wistar大鼠骨髓中的血红素合成以及其激素和垂体激素对垂体切除大鼠血红素合成减少的影响。
Naika Hokan. 1972;19(1):13-23.
9
Hypersecretion of follicle-stimulating hormone (FSH) after ovariectomy of hypophysectomized, pituitary-grafted rats: implications for local regulatory control of FSH.垂体移植的去垂体大鼠卵巢切除术后促卵泡激素（FSH）分泌过多：对FSH局部调节控制的影响
Endocrinology. 1991 Apr;128(4):1731-40. doi: 10.1210/endo-128-4-1731.
10
Effects of hypophysectomy, pituitary gland homogenates and transplants, and prolactin on photoreceptor destruction.垂体切除术、垂体匀浆和移植以及催乳素对光感受器破坏的影响。
Invest Ophthalmol Vis Sci. 1977 Oct;16(10):940-6.

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Growth hormone replacement therapy in growth hormone deficient children and adults: Effects on hemochrome.生长激素缺乏儿童和成人的生长激素替代疗法：对血色素的影响。
J Endocrinol Invest. 2006 May;29(5):399-404. doi: 10.1007/BF03344122.
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Hypopituitarism and anemia: effect of replacement therapy with hydrocortisone and/or levothyroxine.垂体功能减退症与贫血：氢化可的松和/或左甲状腺素替代治疗的效果
J Endocrinol Invest. 2005 Jun;28(6):528-33. doi: 10.1007/BF03347241.
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Effect of long-term treatment with recombinant human growth hormone on erythropoietin secretion in an anemic patient with panhypopituitarism.重组人生长激素长期治疗对一名全垂体功能减退贫血患者促红细胞生成素分泌的影响。
J Endocrinol Invest. 2000 Jan;23(1):31-6. doi: 10.1007/BF03343673.
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EMBO J. 1997 Dec 1;16(23):6926-35. doi: 10.1093/emboj/16.23.6926.