Johnson Ann-Christin, Morata Thais C, Lindblad Ann-Cathrine, Nylén Per R, Svensson Eva B, Krieg Edward, Aksentijevic Aleksandar, Prasher Deepak
Karolinska Institutet, Section of Audiology, Department of Clinical Science, Intervention and Technique, Alfred Nobels Allé 10, S-141 83 Stockholm, Sweden.
Noise Health. 2006 Jan-Mar;8(30):45-57. doi: 10.4103/1463-1741.32467.
Audiological testing, interviews and exposure measurements were used to collect data on the health effects of styrene exposures in 313 workers from fiberglass and metal-product manufacturing plants and a mail terminal. The audiological test battery included pure-tone audiometry, distortion product otoacoustic emissions (DPOAE), psychoacoustic modulation transfer function, interrupted speech, speech recognition in noise and cortical response audiometry (CRA). Workers exposed to noise and styrene had significantly poorer pure-tone thresholds in the high-frequency range (3 to 8 kHz) than the controls, noise-exposed workers and those listed in a Swedish age-specific database. Even though abnormalities were noted on DPOAE and CRA testing, the interrupted speech and speech recognition in noise tests were the more sensitive tests for styrene effects. Further research is needed on the underlying mechanisms to understand the effects of styrene and on audiological test batteries to detect changes in populations exposed to solvents.
通过听力测试、访谈和暴露测量，收集了来自玻璃纤维和金属制品制造工厂以及一个邮件处理终端的313名工人接触苯乙烯对健康影响的数据。听力测试组合包括纯音听力测定、畸变产物耳声发射（DPOAE）、心理声学调制传递函数、中断言语、噪声中的言语识别和皮层反应听力测定（CRA）。接触噪声和苯乙烯的工人在高频范围（3至8千赫）的纯音阈值明显比对照组、仅接触噪声的工人以及瑞典特定年龄数据库中的人群差。尽管在DPOAE和CRA测试中发现了异常，但中断言语和噪声中的言语识别测试对苯乙烯影响更为敏感。需要进一步研究其潜在机制以了解苯乙烯的影响，并研究听力测试组合以检测接触溶剂人群的变化。
