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获得性色素沉着模拟黑斑息肉综合征：弥漫性葡萄膜黑素细胞增生的初始表现

Acquired pigmentation simulating Peutz-Jeghers syndrome: initial manifestation of diffuse uveal melanocytic proliferation.

作者信息

Gass J D, Glatzer R J

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida 33101.

出版信息

Br J Ophthalmol. 1991 Nov;75(11):693-5. doi: 10.1136/bjo.75.11.693.

DOI:10.1136/bjo.75.11.693
PMID:1751469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1042533/
Abstract

A 74-year-old man with an occult carcinoma of the colon developed pigmentation of the mouth and penis typical of the Peutz-Jeghers syndrome as the first manifestation of bilateral diffuse uveal melanocytic proliferation. The simultaneous appearance of extraocular pigmented lesion and those in the uveal tract of both eyes of this patient provides further evidence that bilateral diffuse uveal melanocytic proliferation may be caused by activation of occult melanocytic naevus cells in response to either a hormone-producing carcinoma or to some other common oncogenic stimulus.

摘要

一名患有隐匿性结肠癌的74岁男性，出现了口腔和阴茎色素沉着，这是典型的黑斑息肉综合征表现，也是双侧弥漫性葡萄膜黑素细胞增生的首发症状。该患者眼外色素沉着病变与双眼葡萄膜同时出现，进一步证明双侧弥漫性葡萄膜黑素细胞增生可能是由于隐匿性黑素细胞痣细胞对产生激素的癌或其他常见致癌刺激作出反应而激活所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/84a2b291db4a/brjopthal00573-0056-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/ffd0e5819d77/brjopthal00573-0054-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/353a3d873739/brjopthal00573-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/e72011951b56/brjopthal00573-0055-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/b6f5a1183cea/brjopthal00573-0055-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/f52bf33a14d1/brjopthal00573-0055-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/84a2b291db4a/brjopthal00573-0056-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/ffd0e5819d77/brjopthal00573-0054-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/353a3d873739/brjopthal00573-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/e72011951b56/brjopthal00573-0055-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/b6f5a1183cea/brjopthal00573-0055-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/f52bf33a14d1/brjopthal00573-0055-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/1042533/84a2b291db4a/brjopthal00573-0056-a.jpg

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