Bruins N A, Oswald J E, Morreau H, Kievit J, Pavel S, Smelt A H M
Department of General Internal Medicine and Endocrinology, Leiden University Medical Centre, Leiden, the Netherlands.
Neth J Med. 2007 May;65(5):185-7.
Long-term treatment with minocycline is occasionally associated with the development of black thyroid syndrome in which thyroid cancer is frequently found. Here, we report a patient with cutaneous, pulmonary and thyroid sarcoidosis who developed papillary thyroid carcinoma in the presence of a black thyroid syndrome after being treated with minocycline for 2.5 years.
长期使用米诺环素治疗偶尔会与黑甲状腺综合征的发生相关,在该综合征中经常发现甲状腺癌。在此,我们报告一名患有皮肤、肺部和甲状腺结节病的患者,在接受米诺环素治疗2.5年后出现黑甲状腺综合征,并发生了乳头状甲状腺癌。