[急性呼吸窘迫综合征并发EB病毒肺炎]
[Acute respiratory distress syndrome complicating Ebstein-Barr virus pneumonia].
作者信息
Riachy M, Baaklini C, Ibrahim I, Azar H, Yaghi C, Dabar G, Bazarbachi T, Nasnas R, Karam-Sarkis D, Germanos M, Maacaron N, Khayat G, Choucair J
机构信息
Service de Pneumologie et de Réanimation Médicale, Hôtel Dieu de France, Beyrouth, Liban.
出版信息
Rev Mal Respir. 2007 May;24(5):639-43. doi: 10.1016/s0761-8425(07)91134-1.
INTRODUCTION
In the immuno-competent adult Ebstein-Barr virus (EBV) infection is a self-limiting disease that resolves spontaneously.
CASE REPORT
We report a case of acute respiratory distress syndrome (ARDS) complicating severe EBV pneumonia and requiring prolonged artificial ventilation. The diagnosis was confirmed by specific serology and estimation of the viral load by PCR. Apart from supportive treatment with artificial ventilation the medical treatment included the use of Acyclovir and polyclonal immunoglobulins in the early phase and corticosteroids in the late phase. Recovery was progressive and complete.
CONCLUSION
ARDS can complicate EBV pneumonia in an immuno-competent subject. Its management represents a diagnostic and therapeutic challenge.
引言
在免疫功能正常的成年人中，爱泼斯坦 - 巴尔病毒（EBV）感染是一种自限性疾病，可自发缓解。
病例报告
我们报告一例急性呼吸窘迫综合征（ARDS），该综合征使严重的EBV肺炎复杂化，需要长时间的人工通气。通过特异性血清学检查和PCR检测病毒载量确诊。除了人工通气的支持治疗外，药物治疗包括早期使用阿昔洛韦和多克隆免疫球蛋白，后期使用皮质类固醇。患者逐渐康复且完全恢复。
结论
ARDS可使免疫功能正常的受试者发生EBV肺炎复杂化。其管理是一项诊断和治疗挑战。
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