Koulaouzidis Anastasios, Bhat Shivaram, Moschos John, Tan Chew, De Ramon Ana
Department of Gastroenterology, Warrington Hospital, Warrington.
Ann Hepatol. 2007 Apr-Jun;6(2):119-21.
We present the case of a patient referred to the gastroenterology service for investigation of abnormal liver function tests. She had been taking nitrofurantoin for 16 months as prophylaxis against urinary tract infections. CT scan showed evidence of lung pneumonitis and low attenuation in the liver parenchyma. Nitrofurantoin-induced pneumonitis and hepatotoxicity was diagnosed. The patient responded both clinically and biochemically to withdrawal of nitrofurantoin. This combination of adverse reaction to nitrofurantoin is rare.
我们报告了一例因肝功能检查异常而转诊至胃肠病科的患者。她因预防尿路感染服用呋喃妥因16个月。CT扫描显示有肺部肺炎和肝实质低密度影。诊断为呋喃妥因诱发的肺炎和肝毒性。停用呋喃妥因后，患者在临床和生化方面均有改善。这种呋喃妥因不良反应的组合较为罕见。
