Hruban Ralph H, Takaori Kyoichi, Canto Marcia, Fishman Elliot K, Campbell Kurtis, Brune Kieran, Kern Scott E, Goggins Michael
Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Weinberg Room 2242, 401 North Broadway, Baltimore, MD, USA.
J Hepatobiliary Pancreat Surg. 2007;14(3):255-63. doi: 10.1007/s00534-006-1170-9. Epub 2007 May 29.
Three distinct noninvasive precursor lesions to invasive ductal adenocarcinoma of the pancreas have been described. These include the mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia. The early detection and treatment of these lesions can interrupt the progression of a curable noninvasive precursor to an almost uniformly deadly invasive cancer.
胰腺浸润性导管腺癌有三种不同的非侵袭性前驱病变已被描述。这些包括黏液性囊性肿瘤、导管内乳头状黏液性肿瘤和胰腺上皮内瘤变。这些病变的早期检测和治疗可以中断可治愈的非侵袭性前驱病变发展为几乎一致致命的侵袭性癌症。
