Le Ray C, Carayol M, Bréart G, Goffinet F
Université Pierre et Marie Curie Paris VI, INSERM Unit 149, Epidemiological Research Unit on Perinatal Health and Women's Health, Paris, France.
Acta Obstet Gynecol Scand. 2007;86(6):657-65. doi: 10.1080/00016340701245427.
Estimate the frequency of failure to follow the French consensus guidelines for elective induction, and assess how failure affects the rate of cesarean delivery.
We compared cesarean rates according to mode of onset of labor among 5,046 low-risk patients. Violation of the guidelines was defined as induction before 38 weeks or with a Bishop score <5 or with prostaglandins. The cesarean risk was analysed with a bivariable and then a multivariable analysis, which used a multilevel logistic model.
Women with electively induced and spontaneous labor had identical cesarean rates (4.1%). The guidelines were not followed in 23.2% of elective inductions. The risk of cesarean was higher after induction with a Bishop score <5, than after spontaneous labor (adjusted OR=4.1, 95% CI [1.3-12.9]), while elective induction with a favourable cervix did not increase the cesarean risk. In nulliparas, failure to follow the guidelines tripled the risk of cesarean (adjusted OR=3.2 [1.0-10.2]). On the other hand, elective induction of labor for women with a favourable cervix did not increase the risk of cesarean over the risk with spontaneous labor.
Elective induction does not appear to increase the cesarean rate when the guidelines are met. Electively inducing labor with a low Bishop score increased the risk of cesarean, especially in nulliparas.
评估未遵循法国择期引产共识指南的频率,并评估未遵循指南如何影响剖宫产率。
我们比较了5046例低风险患者中根据分娩发动方式的剖宫产率。违反指南的定义为在38周前引产、Bishop评分<5或使用前列腺素引产。采用双变量分析,然后使用多水平逻辑模型进行多变量分析来分析剖宫产风险。
择期引产和自然分娩的女性剖宫产率相同(4.1%)。23.2%的择期引产未遵循指南。Bishop评分<5引产术后的剖宫产风险高于自然分娩(校正比值比=4.1,95%可信区间[1.3-12.9]),而宫颈条件良好的择期引产并未增加剖宫产风险。在初产妇中,未遵循指南使剖宫产风险增加两倍(校正比值比=3.2[1.0-10.2])。另一方面,宫颈条件良好的女性择期引产与自然分娩相比,并未增加剖宫产风险。
当符合指南时,择期引产似乎不会增加剖宫产率。Bishop评分低时择期引产会增加剖宫产风险,尤其是在初产妇中。