Shah Mona, Zhu Kangmin, Palmer Richard C, Jatoi Ismail, Shriver Craig, Wu Hongyu
United States Military Cancer Institute, Walter Reed Army Medical Center, Washington, DC, USA.
J Womens Health (Larchmt). 2007 May;16(4):526-34. doi: 10.1089/jwh.2006.0108.
Several national medical organizations recommend more intensive screening or screening at an earlier age for individuals with a family history of breast, colorectal, or skin cancer. This study examined whether women with a family history of cancer were more likely to use breast, colorectal, or skin cancer screenings compared with those without such a family history.
The data for this study came from female respondents who participated in the 2000 National Health Interview Survey. The age range of the study subjects and the definitions of cancer screening were determined based on the American Cancer Society recommendations on cancer screening.
When compared with women without a family history of breast cancer, women with a family history were more likely to undergo a screening mammogram. Women who had a family history of colorectal cancer were twice as likely to use colorectal cancer screening than women without a family history of colorectal cancer. The association of family history with colorectal and breast cancer screening was stronger among the younger age group for which a screening test is recommended if one has such a family history. The association between skin cancer screening and family history of skin cancer was significant only in younger women.
Women with a family history of cancer were more likely to have colorectal, breast, and skin cancer screening examinations. This may be a result of more physicians' recommendations and higher personal motivation for getting cancer screening, suggesting that the efficacy of national guidelines has been increasing somewhat.
几个国家医学组织建议,对于有乳腺癌、结直肠癌或皮肤癌家族史的个体,应进行更密集的筛查或在更早年龄进行筛查。本研究调查了有癌症家族史的女性与没有此类家族史的女性相比,是否更有可能进行乳腺癌、结直肠癌或皮肤癌筛查。
本研究的数据来自参与2000年全国健康访谈调查的女性受访者。研究对象的年龄范围和癌症筛查的定义是根据美国癌症协会关于癌症筛查的建议确定的。
与没有乳腺癌家族史的女性相比,有家族史的女性更有可能接受乳腺钼靶筛查。有结直肠癌家族史的女性进行结直肠癌筛查的可能性是没有结直肠癌家族史女性的两倍。在较年轻的年龄组中,如果有家族史建议进行筛查检测,家族史与结直肠癌和乳腺癌筛查之间的关联更强。皮肤癌筛查与皮肤癌家族史之间的关联仅在年轻女性中显著。
有癌症家族史的女性更有可能进行结直肠癌、乳腺癌和皮肤癌筛查检查。这可能是由于更多医生的建议以及更高的个人进行癌症筛查的积极性,这表明国家指南的效力在一定程度上有所提高。