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心脏移植:心力衰竭死亡风险评估

Heart transplantation: assessment of heart failure mortality risk.

作者信息

Matthews Jennifer Cowger, Dardas Todd F, Aaronson Keith D

机构信息

Division of Cardiovascular Medicine, University of Michigan Medical Center, Women's L3623, Ann Arbor, MI 48109-0271, USA.

出版信息

Curr Heart Fail Rep. 2007 Jun;4(2):103-9. doi: 10.1007/s11897-007-0008-3.

DOI:10.1007/s11897-007-0008-3
PMID:17521503
Abstract

Heart failure (HF) presents with a wide spectrum of disease severity and with a broad risk of associated morbidity and mortality. Identification of individuals at high risk for HF death is important for assessment of candidacy for heart transplantation and mechanical circulatory assistance and, more broadly, for guiding pharmaceutical, surgical, or palliative interventions. In this article, we review and compare several of the HF risk prediction tools currently available, highlighting their clinical utilities and potential shortcomings. Risk prediction tools must be carefully selected, recognizing that their accuracy is likely to be greatest when used in patients most similar to those from whom the tool was developed. As HF is a dynamic condition, serial risk assessment at regular intervals and as patient clinical status changes is warranted, although clinical evidence to support this practice is limited.

摘要

心力衰竭(HF)具有广泛的疾病严重程度范围以及相关发病和死亡的广泛风险。识别HF死亡高风险个体对于评估心脏移植和机械循环辅助的候选资格很重要,更广泛地说,对于指导药物、手术或姑息性干预也很重要。在本文中,我们回顾并比较了目前可用的几种HF风险预测工具,突出了它们的临床实用性和潜在缺点。必须谨慎选择风险预测工具,要认识到当在与开发该工具的患者最相似的患者中使用时,其准确性可能最高。由于HF是一种动态病症,尽管支持这种做法的临床证据有限,但定期以及随着患者临床状态变化进行连续风险评估是必要的。

相似文献

1
Heart transplantation: assessment of heart failure mortality risk.心脏移植:心力衰竭死亡风险评估
Curr Heart Fail Rep. 2007 Jun;4(2):103-9. doi: 10.1007/s11897-007-0008-3.
2
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本文引用的文献

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Exercise and heart failure: assessment and treatment.运动与心力衰竭:评估与治疗
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Validation of peak exercise oxygen consumption and the Heart Failure Survival Score for serial risk stratification in advanced heart failure.晚期心力衰竭连续风险分层中峰值运动耗氧量及心力衰竭生存评分的验证
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Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis.急性失代偿性心力衰竭住院死亡率的风险分层:分类与回归树分析
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Heart failure survival score continues to predict clinical outcomes in patients with heart failure receiving beta-blockers.心力衰竭生存评分持续预测接受β受体阻滞剂治疗的心力衰竭患者的临床结局。
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Cardiopulmonary exercise testing and prognosis in chronic heart failure: a prognosticating algorithm for the individual patient.慢性心力衰竭的心肺运动试验与预后:个体患者的预后评估算法
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Selection of patients for heart transplantation in the current era of heart failure therapy.当前心力衰竭治疗时代心脏移植患者的选择
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