Lanier Lewis L
Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143-0414, USA.
Eur J Immunol. 2007 Jun;37(6):1424-6. doi: 10.1002/eji.200737418.
In this issue of the European Journal of Immunology (EJI), Stewart et al. report about a population of gammadelta-T cells expressing an extensive repertoire of NK cell receptors, and the presence of non-rearranged germline TCRdelta transcripts in conventional NK cells. These findings and other recent studies highlight the similarities of NK cells and T cells and the problems in discriminating between these two lineages.
在本期《欧洲免疫学杂志》(EJI)中,斯图尔特等人报道了一群表达广泛自然杀伤(NK)细胞受体库的γδ-T细胞,以及常规NK细胞中存在未重排的种系TCRδ转录本。这些发现以及其他近期研究突出了NK细胞和T细胞的相似性,以及区分这两个谱系时存在的问题。