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大鼠感觉条件反射中的年龄相关差异。

Age-related differences in sensory conditioning in rats.

作者信息

Chen W J, Lariviere N A, Heyser C J, Spear L P, Spear N E

机构信息

Center for Developmental Psychobiology, State University of New York, Binghamton 13902.

出版信息

Dev Psychobiol. 1991 Jul;24(5):307-26. doi: 10.1002/dev.420240502.

DOI:10.1002/dev.420240502
PMID:1752352
Abstract

Four experiments tested rats 8, 12, or 21 days postnatal for sensory conditioning in terms of the association acquired between two odors presented simultaneously or sequentially. The sensory conditioning of 8- and 12-day-old rats exceeded that of rats 21 days of age when the odors were presented simultaneously. When one odor was presented immediately followed by another, however, 21-day-old rats conditioned as effectively as the younger animals, and with a sufficiently long interval between odors (20 min), the sensory conditioning of the 21-day-old rats surpassed that of the rats 12 days of age. Although consistent across a variety of procedures, in previous experiments and within the present study, the age-related differences in sensory conditioning after simultaneous presentation of two odors are difficult to understand. Increasing knowledge of the ontogeny of orienting may lead to an explanation in terms of Thompson's (1972) theory linking sensory conditioning with orienting and sensitization.

摘要

四项实验对出生后8天、12天或21天的大鼠进行了感觉条件反射测试,测试内容是关于同时或相继呈现的两种气味之间形成的关联。当同时呈现气味时,8日龄和12日龄大鼠的感觉条件反射超过了21日龄的大鼠。然而,当一种气味紧接着另一种气味呈现时,21日龄大鼠的条件反射效果与年幼动物一样好,并且当气味之间的间隔足够长(20分钟)时,21日龄大鼠的感觉条件反射超过了12日龄的大鼠。尽管在各种实验程序中都是一致的,在之前的实验以及本研究中,同时呈现两种气味后感觉条件反射中与年龄相关的差异很难理解。对定向发生学的了解不断增加,可能会根据汤普森(1972年)将感觉条件反射与定向和敏感化联系起来的理论给出解释。

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Age-related differences in sensory conditioning in rats.大鼠感觉条件反射中的年龄相关差异。
Dev Psychobiol. 1991 Jul;24(5):307-26. doi: 10.1002/dev.420240502.
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