Bodé S, Hassager C, Gudmand-Høyer E, Christiansen C
Department of Medical Gastroenterology, Gentofte Hospital, Copenhagen, Denmark.
Gut. 1991 Nov;32(11):1342-5. doi: 10.1136/gut.32.11.1342.
Twenty two treated adult patients with coeliac disease (aged 20-70 years) were examined. Body composition was assessed from anthropometry and directly measured by dual photon absorptiometry. Bone mineral content was measured in the spine (dual photon absorptiometry) and at two forearm sites (single photon absorptiometry). Compared with age matched healthy subjects, treated coeliac patients had lower body mass index (-5%, p less than 0.05) and lower directly measured total body fat mass (-30%, p less than 0.001). They also had decreased bone mineral content (-9 to -13%, p less than 0.01) in the spine and in the forearms. The serum concentrations of albumin, D vitamin binding protein, and iron were reduced (-6 to -22%, p less than 0.01), but otherwise blood and urine analyses were normal. We conclude that this group of treated adult coeliac patients had a reduced fat mass and bone mineral content compared with the general population.
对22名接受治疗的成年乳糜泻患者（年龄在20至70岁之间）进行了检查。通过人体测量评估身体成分，并通过双能光子吸收法直接测量。在脊柱（双能光子吸收法）和两个前臂部位（单能光子吸收法）测量骨矿物质含量。与年龄匹配的健康受试者相比，接受治疗的乳糜泻患者体重指数较低（-5%，p<0.05），直接测量的全身脂肪量较低（-30%，p<0.001）。他们脊柱和前臂的骨矿物质含量也降低了（-9%至-13%，p<0.01）。血清白蛋白、维生素D结合蛋白和铁的浓度降低了（-6%至-22%，p<0.01），但血液和尿液分析在其他方面正常。我们得出结论，与普通人群相比，这组接受治疗的成年乳糜泻患者的脂肪量和骨矿物质含量降低。
