Collins B J, Bell P M, Thomson J M, Fee D B, Wilson E A, Love A H
J R Soc Med. 1986 Apr;79(4):206-9. doi: 10.1177/014107688607900406.
The gluten content and nutritional adequacy of the diet of a group of adult coeliac patients supposedly following a gluten-free diet for at least one year were assessed. Results were considered in relation to the nutritional state of these patients, determined by anthropometric measurement, and the histological appearance of jejunal biopsies taken at the time of nutritional assessment. Imperfect gluten avoidance, mild malnutrition and mild histological abnormalities on jejunal biopsy were frequent findings. A careful dietary and nutritional assessment when considered in light of histological findings at jejunal biopsy helps to identify the causes of persisting symptoms or malnutrition in treated coeliac patients. A normal jejunal biopsy in a malnourished patient whose dietary compliance is good should prompt a search for an alternative diagnosis.
对一组成年乳糜泻患者的饮食中的麸质含量和营养充足性进行了评估,这些患者据称遵循无麸质饮食至少一年。根据人体测量确定的这些患者的营养状况以及在营养评估时进行的空肠活检的组织学表现来考虑结果。经常发现麸质避免不彻底、轻度营养不良以及空肠活检出现轻度组织学异常。根据空肠活检的组织学结果进行仔细的饮食和营养评估,有助于确定经治疗的乳糜泻患者持续出现症状或营养不良的原因。对于饮食依从性良好但营养不良的患者,空肠活检结果正常应促使寻找其他诊断。