隧道式巩膜切口预防玻璃体内注射后玻璃体反流。
Tunneled scleral incision to prevent vitreal reflux after intravitreal injection.
作者信息
Rodrigues Eduardo B, Meyer Carsten H, Grumann Astor, Shiroma Helio, Aguni Jonathan S, Farah Michel E
机构信息
Retina Department, Hospital Regional São Jose, Centro Oftalmológico, Florianópolis, Brazil.
出版信息
Am J Ophthalmol. 2007 Jun;143(6):1035-7. doi: 10.1016/j.ajo.2007.01.035.
PURPOSE
To investigate the efficacy of tunneled scleral incision compared with standard straight scleral incision to prevent vitreal reflux after intravitreal (IVT) injection.
DESIGN
Prospective comparative controlled nonrandomized clinical study.
METHODS
Eighty-eight eyes undergoing IVT-injection were allocated into four groups to compare the vitreal reflux after injection of 0.1 ml of triamcinolone acetonide (TA) and Avastin using a tunneled vs straight injection technique. The amount of intraoperative drug reflux was estimated by measuring the width of the subconjunctival bleb.
RESULTS
The mean measured reflux of volume was statistically less with the tunneled scleral incision (1.13 mm standard deviation [SD] +/- 1.16 for TA; 1.13 mm SD +/- 1.39 for Avastin) than in eyes undergoing the straight scleral injection (3.00 mm SD +/- 1.77 for TA; 3.18 mm SD +/- 1.68 for Avastin) for both Avastin and TA IVT-injections groups (P < .001).
CONCLUSIONS
The tunneled scleral incision promotes statistically significant less vitreal reflux for IVT drug injection.
目的
研究隧道式巩膜切口与标准直巩膜切口相比，在玻璃体内（IVT）注射后预防玻璃体反流的效果。
设计
前瞻性对比对照非随机临床研究。
方法
88只接受IVT注射的眼睛被分为四组，采用隧道式与直入式注射技术，比较注射0.1毫升曲安奈德（TA）和阿瓦斯汀后玻璃体反流情况。通过测量结膜下气泡宽度评估术中药物反流量。
结果
对于TA和阿瓦斯汀IVT注射组，隧道式巩膜切口组平均测量的反流体积在统计学上低于直巩膜注射组（TA组为1.13毫米标准差[SD]±1.16；阿瓦斯汀组为1.13毫米SD±1.39）（直巩膜注射组TA为3.00毫米SD±1.77；阿瓦斯汀为3.18毫米SD±1.68）（P <.001）。
结论
对于IVT药物注射，隧道式巩膜切口在统计学上能显著减少玻璃体反流。
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