Cotter Susan A, Edwards Allison R, Arnold Robert W, Astle William F, Barnhardt Carmen N, Beck Roy W, Birch Eileen E, Donahue Sean P, Everett Donald F, Felius Joost, Holmes Jonathan M, Kraker Raymond T, Melia B Michele, Repka Michael X, Wallace David K, Weise Katherine K
Jaeb Center for Health Research, 15310 Amberly Drive, Suite 350, Tampa, FL 33647, USA.
Am J Ophthalmol. 2007 Jun;143(6):1060-3. doi: 10.1016/j.ajo.2007.02.029.
To report data on the response of previously untreated strabismic amblyopia to spectacle correction.
Prospective, interventional case series.
Twelve patients with previously untreated strabismic amblyopia were prescribed spectacles and examined at five-week intervals until visual acuity was not improved from the prior visit.
Amblyopic eye acuity improved by 2 lines or more from spectacle-corrected baseline acuity in nine of the 12 patients (75%), resolving in three (interocular difference <or=1 line). Mean change from baseline to maximum improvement was 2.2 +/- 1.8 lines. Improvement continued for up to 25 weeks.
These results support the suggestion from a prior study that strabismic amblyopia can improve and even resolve with spectacle correction alone. Larger studies with concurrent controls are needed to confirm or refute these findings.
报告关于未经治疗的斜视性弱视对眼镜矫正反应的数据。
前瞻性干预性病例系列研究。
为12例未经治疗的斜视性弱视患者开具眼镜处方,并每隔5周进行检查,直至视力较上次检查无改善。
12例患者中有9例(75%)弱视眼视力较眼镜矫正后的基线视力提高了2行或更多,其中3例视力恢复正常(双眼视力差异≤1行)。从基线到最大改善程度的平均变化为2.2±1.8行。改善持续长达25周。
这些结果支持了先前一项研究的建议,即斜视性弱视仅通过眼镜矫正即可改善甚至治愈。需要开展有同期对照的更大规模研究来证实或反驳这些发现。