Mensink Peter B F, Geelkerken Robert H, Huisman Ad B, Kuipers Ernst J, Kolkman Jeroen J
Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.
Dig Dis Sci. 2008 Jan;53(1):133-9. doi: 10.1007/s10620-007-9833-1. Epub 2007 May 26.
Gastrointestinal tonometry is currently the only clinical diagnostic test that enables identification of symptomatic chronic gastrointestinal ischemia. Gastric exercise tonometry has proven its value for detection of ischemia in this patients group, but has its disadvantages. Earlier studies with postprandial tonometry gave unreliable results. In this study we challenged (again) the use of postprandial tonometry in patients suspected of gastrointestinal ischemia.
Patients suspected for chronic gastrointestinal ischemia had standard diagnostic work up, including gastric exercise tonometry and 24-h tonometry using standard meals.
Thirty-three patients were enrolled in the study. Chronic gastrointestinal ischemia was diagnosed in 17 (52%) patients. The 24-h tonometry correctly predicted the presence of ischemia in 13/17 patients, and absence of ischemia in 15/16 patients.
The use of 24-h tonometry after meals in patients suspected of gastrointestinal ischemia seems feasible, with promising accuracy for the detection of ischemia.
胃肠道张力测定法是目前唯一能够识别有症状的慢性胃肠道缺血的临床诊断测试。胃运动张力测定法已在该患者群体中证明其对缺血检测的价值,但也有其缺点。早期关于餐后张力测定法的研究结果不可靠。在本研究中,我们再次对疑似胃肠道缺血患者使用餐后张力测定法提出质疑。
疑似慢性胃肠道缺血的患者接受了包括胃运动张力测定法和使用标准餐食进行24小时张力测定法在内的标准诊断检查。
33名患者纳入本研究。17名(52%)患者被诊断为慢性胃肠道缺血。24小时张力测定法正确预测了17名患者中13名存在缺血,以及16名患者中15名不存在缺血。
对疑似胃肠道缺血的患者使用餐后24小时张力测定法似乎可行,对缺血检测具有可观的准确性。