Feldman2 S, Conforti N, Chowers I
Neuroendocrinology. 1975;18(4):359-65. doi: 10.1159/000122416.
Previous experiments from this laboratory using the hypothalamic island have demonstrated that the adrenocortical discharge following sciatic nerve stimulation is mediated by neural pathways only. With the purpose of identifying the neural structures involved, this response was studied in rats with bilateral lesions in the medial forebrain bundle (MFB), mammillary peduncle (MP), fasciculus longitudinalis dorsalis (FLD), midbrain reticular formation MRF) and the medial geniculate body (GM). Lesions in the MFB, MP and MRF have inhibited the adrenocortical response following sciatic nerve stimulation. These and other data indicate that the above structures are involved in the mediation of this response and that the afferent pathway enters the mediobasal hypothalamus anteriorly.
该实验室先前利用下丘脑岛进行的实验已证明，坐骨神经刺激后肾上腺皮质的放电仅由神经通路介导。为了确定其中涉及的神经结构，对内侧前脑束（MFB）、乳头脚（MP）、背侧纵束（FLD）、中脑网状结构（MRF）和内侧膝状体（GM）双侧受损的大鼠的这种反应进行了研究。MFB、MP和MRF的损伤抑制了坐骨神经刺激后的肾上腺皮质反应。这些以及其他数据表明，上述结构参与了这种反应的介导，且传入通路从前进入下丘脑内侧基底部。
