丘脑底核脑深部电刺激术的手术及硬件并发症
Surgical and hardware complications in subthalamic nucleus deep brain stimulation.
作者信息
Chou Yu-Cheng, Lin Shinn-Zong, Hsieh Wanhua Annie, Lin Sheng Huang, Lee Chao Chin, Hsin Yue Long, Yen Pao-Sheng, Lee Chi Wei, Chiu Wen-Ta, Chen Shin-Yuan
机构信息
Division of Functional Neuroscience, Tzu Chi General Hospital, Tzu Chi University, Hualien, Taiwan.
出版信息
J Clin Neurosci. 2007 Jul;14(7):643-9. doi: 10.1016/j.jocn.2006.02.016.
OBJECTIVE
To assess the surgical and hardware complications in 26 consecutive patients with movement disorders undergoing subthalamic deep brain stimulation (STN-DBS) in early practice at our institute.
METHODS
The 26 patients in our institute were analyzed retrospectively. Group A included the first eight patients treated while we had no facility for microelectrode recording (MER), 16 intracranial procedures were performed and 8 batteries were implanted. Group B (with MER) included 18 patients, 35 intracranial procedures were performed and 18 batteries were implanted.
RESULTS
The intracranial morbidity was 18.75% in group A and 5.71% in group B. The extracranial morbidity was 37.5% in group A and 16.67% in group B. There was no hardware-related infection in our study. The overall mortality rate was 7.69%, and deaths were not surgical related.
CONCLUSIONS
The associated morbidity is significant in STN-DBS. The use of MER may improve the clinical outcome while decreasing the morbidity.
目的
评估我院早期连续26例接受丘脑底核脑深部电刺激术（STN - DBS）治疗的运动障碍患者的手术及硬件相关并发症。
方法
对我院26例患者进行回顾性分析。A组包括最初8例在我们没有微电极记录（MER）设备时接受治疗的患者，进行了16次颅内手术并植入8个电池。B组（有MER）包括18例患者，进行了35次颅内手术并植入18个电池。
结果
A组颅内并发症发生率为18.75%，B组为5.71%。A组颅外并发症发生率为37.5%，B组为16.67%。本研究中未发生与硬件相关的感染。总死亡率为7.69%，死亡与手术无关。
结论
STN - DBS相关并发症较为显著。使用MER可能在降低并发症发生率的同时改善临床结局。
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