Suppr超能文献

支气管扩张对哮喘临床表现的影响。

The impact of bronchiectasis in clinical presentation of asthma.

作者信息

Oguzulgen I Kivilcim, Kervan Firdevs, Ozis Turkan, Turktas Haluk

机构信息

Gazi University School of Medicine, Department of Pulmonary Medicine, Ankara, Turkey.

出版信息

South Med J. 2007 May;100(5):468-71. doi: 10.1097/SMJ.0b013e31802fa16f.

Abstract

BACKGROUND

Though asthma and bronchiectasis are two different diseases, their coexistence has been shown in many patients. The aim of this study was to evaluate the clinical features of asthmatics with bronchiectasis compared with pure asthmatics.

METHODS

We evaluated 1680 asthmatics followed-up in our clinic. Fifty-one asthmatics had the diagnosis of bronchiectasis. These patients were compared with fifty-one age and gender matched asthmatics without bronchiectasis.

RESULTS

The prevalence of bronchiectasis among the asthmatics was 3%. Asthma diagnosis was made at the age of 33.2 +/- 16.8 years for asthmatics with bronchiectasis and 39.5 +/- 16.2 years for pure asthmatics (P = 0.05). Asthmatics with bronchiectasis mostly had severe persistent asthma (49.0%), while pure asthmatics mostly had mild persistent and intermittent asthma (69.4%). History of hospitalization due to severe asthma exacerbation and presence of chronic respiratory failure was significantly higher in bronchiectatic group.

CONCLUSIONS

These data show that bronchiectasis can contribute to severe and difficult to control asthma with pulmonary complications like chronic respiratory failure.

摘要

背景

尽管哮喘和支气管扩张是两种不同的疾病,但在许多患者中已发现它们并存。本研究的目的是评估合并支气管扩张的哮喘患者与单纯哮喘患者相比的临床特征。

方法

我们评估了在我们诊所随访的1680例哮喘患者。其中51例哮喘患者被诊断为支气管扩张。将这些患者与51例年龄和性别匹配的无支气管扩张的哮喘患者进行比较。

结果

哮喘患者中支气管扩张的患病率为3%。合并支气管扩张的哮喘患者哮喘诊断年龄为33.2±16.8岁,单纯哮喘患者为39.5±16.2岁(P = 0.05)。合并支气管扩张的哮喘患者大多为重度持续性哮喘(49.0%),而单纯哮喘患者大多为轻度持续性和间歇性哮喘(69.4%)。支气管扩张组因严重哮喘加重而住院的病史及慢性呼吸衰竭的发生率明显更高。

结论

这些数据表明,支气管扩张可导致严重且难以控制的哮喘,并伴有慢性呼吸衰竭等肺部并发症。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验