Xu L, Wang Y, Jonas J B
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
Eur J Ophthalmol. 2007 May-Jun;17(3):459-60. doi: 10.1177/112067210701700335.
To determine the incidence of optic nerve damage due to nonarteritic anterior ischemic optic neuropathy (NAION) in the adult Chinese population.
The Beijing Eye Study, a population-based, longitudinal study which included 4439 subjects (age 40+ years) in 2006, was repeated in 2006. In the follow-up examination, 3169 (71.4%) subjects participated. Optic disc photographs were assessed. Diagnostic criteria for incident NAION were a small optic disc, segmental pallor, and loss of retinal nerve fiber layer and visual field in the follow-up examination, with a normal optic nerve head appearance at baseline.
New NAION was found in one eye, with an incidence rate of 0.03+/-0.03% per 5 years (mean +/- standard error) (95% confidence interval: -0.03, 0.09), or about 1:16,000 subjects per year.
Within a 5-year period, new NAION may develop in 1 out of 3200 adult Chinese, or 1:16,000 adult Chinese per year.
确定成年中国人群中非动脉炎性前部缺血性视神经病变（NAION）所致视神经损伤的发病率。
基于人群的纵向研究——北京眼病研究于2006年纳入了4439名年龄40岁及以上的受试者，并于2006年进行了重复研究。在随访检查中，3169名（71.4%）受试者参与。对视盘照片进行了评估。NAION发病的诊断标准为随访检查中视盘小、节段性苍白、视网膜神经纤维层及视野缺损，且基线时视神经乳头外观正常。
一只眼睛发现了新发NAION，每5年的发病率为0.03±0.03%（均值±标准误）（95%置信区间：-0.03，0.09），即每年约1/16000的受试者。
在5年时间内，每3200名成年中国人中可能有1人发生新发NAION, 即每年每16000名成年中国人中有1人发病。
