中国成年人非动脉炎性前部缺血性视神经病变的发病率：北京眼病研究

Incidence of nonarteritic anterior ischemic optic neuropathy in adult Chinese: the Beijing Eye Study.

作者信息

Xu L, Wang Y, Jonas J B

机构信息

Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.

出版信息

Eur J Ophthalmol. 2007 May-Jun;17(3):459-60. doi: 10.1177/112067210701700335.

DOI:10.1177/112067210701700335

PMID:17534837

Abstract

PURPOSE

To determine the incidence of optic nerve damage due to nonarteritic anterior ischemic optic neuropathy (NAION) in the adult Chinese population.

METHODS

The Beijing Eye Study, a population-based, longitudinal study which included 4439 subjects (age 40+ years) in 2006, was repeated in 2006. In the follow-up examination, 3169 (71.4%) subjects participated. Optic disc photographs were assessed. Diagnostic criteria for incident NAION were a small optic disc, segmental pallor, and loss of retinal nerve fiber layer and visual field in the follow-up examination, with a normal optic nerve head appearance at baseline.

RESULTS

New NAION was found in one eye, with an incidence rate of 0.03+/-0.03% per 5 years (mean +/- standard error) (95% confidence interval: -0.03, 0.09), or about 1:16,000 subjects per year.

CONCLUSIONS

Within a 5-year period, new NAION may develop in 1 out of 3200 adult Chinese, or 1:16,000 adult Chinese per year.

摘要

目的

确定成年中国人群中非动脉炎性前部缺血性视神经病变（NAION）所致视神经损伤的发病率。

方法

基于人群的纵向研究——北京眼病研究于2006年纳入了4439名年龄40岁及以上的受试者，并于2006年进行了重复研究。在随访检查中，3169名（71.4%）受试者参与。对视盘照片进行了评估。NAION发病的诊断标准为随访检查中视盘小、节段性苍白、视网膜神经纤维层及视野缺损，且基线时视神经乳头外观正常。