Verdellen Cara W J, Hoogduin Cees A L, Keijsers Ger P J
Department of Clinical Psychology, Radboud University Nijmegen, Nijmegen, The Netherlands.
Mov Disord. 2007 Aug 15;22(11):1601-6. doi: 10.1002/mds.21577.
Exposure and response prevention (ER), a behavioral treatment program consisting of exposure to premonitory sensory experiences during prolonged tic suppression, was shown to be a promising new treatment for tics in Tourette's syndrome (TS). In this study, the commonly reported paradoxical increase in tic frequency following voluntary tic suppression, i.e., rebound phenomenon, was examined. Tic frequency was rated in 20 TS patients during 15-minute videotaped conversations taken both before and following 10 ER sessions. In addition, tic frequency was obtained at home by family members of the patients during 15-minute daily tic frequency registrations. Ratings following ER sessions were compared with ratings obtained before the sessions. Neither the ratings at the institute nor the ratings at home supported a rebound effect following ER tic suppression.
暴露与反应预防（ER）是一种行为治疗方案，包括在长时间抑制抽动期间暴露于先兆性感觉体验，已被证明是治疗抽动秽语综合征（TS）抽动症状的一种有前景的新疗法。在本研究中，对自愿抑制抽动后常见的抽动频率反常增加现象，即反弹现象进行了研究。在10次ER治疗前后，对20名TS患者进行15分钟录像对话期间的抽动频率进行评分。此外，患者家属在患者每日15分钟的抽动频率记录期间在家中获取抽动频率。将ER治疗后的评分与治疗前获得的评分进行比较。无论是在研究所的评分还是在家中的评分，均不支持ER抽动抑制后的反弹效应。
