异位性胃黏膜（入口斑）：内镜检出率、组织病理学、人口统计学和临床特征。
Heterotopic gastric mucosa (inlet patch): endoscopic prevalence, histopathological, demographical and clinical characteristics.
机构信息
Department of Internal Medicine, Division of Gastroenterology, Medical Center, Firat University, Elazig, Turkey.
出版信息
Int J Clin Pract. 2009 Feb;63(2):287-91. doi: 10.1111/j.1742-1241.2006.01215.x. Epub 2007 May 29.
OBJECTIVE
Heterotopic gastric mucosa (HGM) is found in the cervical oesophagus, just below the upper oesophageal sphincter, and has generally been overlooked by endoscopists. The objective of the present study is to determine endoscopic prevalence and histopathological and clinical characteristics of HGM and to classify patients according to their clinicopathological features.
METHOD
A total of 911 consecutive patients (436 M and 475 F) who were admitted to our Endoscopy Unit were examined. HGM type and the presence of Helicobacter pylori (Hp) either in the stomach or in the HGM were histopathologically evaluated.
RESULTS
Of the 911 patients, 33 (25 M and 8 F) were found to have HGM. HGM prevalence was determined to be 3.6%. On the basis of HGM patients' symptoms, only dysphagia was significantly correlated with the size of HGM (p < 0.05). Hp was positive in 29.2% of HGM. Clinicopathological classification of the patients showed that 20 patients were HGM type 1 and 13 were HGM type 2. None of the patients had HGM type 3, 4 or 5.
CONCLUSION
Prevalence of HGM was 3.6%. Dysphagia was found related with the size of HGM. This may be associated with larger HGMs' causing more acid secretion.
目的
异位胃黏膜（HGM）位于食管颈段，刚好在食管上括约肌的下方，通常被内镜医生忽视。本研究旨在确定 HGM 的内镜检出率及组织病理学和临床特征，并根据其临床病理特征对患者进行分类。
方法
对我院内镜科收治的 911 例连续患者（男 436 例，女 475 例）进行检查。通过组织病理学评估 HGM 的类型以及 HGM 中是否存在幽门螺杆菌（Hp）。
结果
911 例患者中，33 例（男 25 例，女 8 例）存在 HGM。HGM 的检出率为 3.6%。根据 HGM 患者的症状，仅吞咽困难与 HGM 的大小呈显著相关（p < 0.05）。在 HGM 患者中，Hp 阳性率为 29.2%。对患者进行临床病理分类后显示，20 例为 HGM 1 型，13 例为 HGM 2 型。无一例患者为 HGM 3 型、4 型或 5 型。
结论
HGM 的检出率为 3.6%。吞咽困难与 HGM 的大小有关。这可能与较大的 HGM 导致更多胃酸分泌有关。
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