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[药物治疗及其联合高压氧和血液吸附对稳定型心绞痛疗效的比较研究]

[Comparative study of the effect of drug therapy and its combination with hyperbaric oxygenation and hemosorption on stable angina pectoris].

作者信息

Markarian S S, Shirinskaia G I, Starostin S G, Zagvozkin V N

出版信息

Kardiologiia. 1991 Sep;31(9):40-2.

PMID:1753612
Abstract

Seventy seven males aged under 60 years with Functional Classes II-IV stable angina were examined. The patients were randomly divided into 3 groups: 1) 24 patients receiving drug therapy alone; 2) 27 patients taking drug therapy in combination with hyperbaric oxygenation; and 3) 26 patients having drug therapy in combination with hemosorption. In all the patient groups, there was a reduction in the frequency of resting and exercise anginal attacks, in Group 3, exercise tolerance was increased due to drug therapy. In a re-examination, there was a significant fall in total cholesterol and high-density lipoprotein cholesterol levels only in Group 3. A comparison of daily drug doses indicated that the functional class improved only due to the adequate antianginal therapy. Thus, hyperbaric oxygenation and hemosorption have no significant action on the degree of stable angina.

摘要

对77名年龄在60岁以下、心功能II-IV级的稳定型心绞痛男性患者进行了检查。患者被随机分为3组:1)24名仅接受药物治疗的患者;2)27名接受药物治疗联合高压氧治疗的患者;3)26名接受药物治疗联合血液吸附的患者。在所有患者组中,静息和运动性心绞痛发作的频率均有所降低,在第3组中,由于药物治疗,运动耐量有所提高。在复查中,仅第3组的总胆固醇和高密度脂蛋白胆固醇水平显著下降。每日药物剂量的比较表明,功能分级仅因充分的抗心绞痛治疗而改善。因此,高压氧治疗和血液吸附对稳定型心绞痛的程度没有显著作用。

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[Comparative study of the effect of drug therapy and its combination with hyperbaric oxygenation and hemosorption on stable angina pectoris].[药物治疗及其联合高压氧和血液吸附对稳定型心绞痛疗效的比较研究]
Kardiologiia. 1991 Sep;31(9):40-2.
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