Childs Sharon G
Adult/Acute Care Nurse Practitioner, Baltimore, MD, USA.
Orthop Nurs. 2007 May-Jun;26(3):175-82; quiz 183-4. doi: 10.1097/01.NOR.0000276969.09808.2c.
Tendon rupture related to trauma and corticosteroid injection, in and about tendon insertion sites, is well documented in the literature. Rupture of tendon after fluoroquinolone therapy has been identified in the recent past. Both short- and long-term courses of antibiotic treatment with fluoroquinolone may precipitate alteration in tendon matrix leading to tendinopathy with subsequent rupture. The pathogenesis of tendon rupture secondary to fluoroquinolone therapy is presented.
与创伤和皮质类固醇注射相关的肌腱断裂，在肌腱附着部位及其周围，在文献中有充分记载。近期已发现氟喹诺酮治疗后肌腱断裂的情况。氟喹诺酮短期和长期抗生素治疗疗程均可能促使肌腱基质发生改变，导致肌腱病并随后发生断裂。本文阐述了氟喹诺酮治疗继发肌腱断裂的发病机制。
