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情绪变化可预测银屑病患者在情感表露后疾病的活动情况及生活质量。

Changes in mood predict disease activity and quality of life in patients with psoriasis following emotional disclosure.

作者信息

Vedhara Kavita, Morris Rona Moss, Booth Roger, Horgan Miriam, Lawrence Mandy, Birchall Nicholas

机构信息

MRC Health Services Research Collaboration, University of Bristol, Bristol, United Kingdom.

出版信息

J Psychosom Res. 2007 Jun;62(6):611-9. doi: 10.1016/j.jpsychores.2006.12.017.

Abstract

OBJECTIVE

The present study examined the effects of emotional disclosure (ED) intervention on both disease severity and quality of life in patients with psoriasis.

METHODS

Fifty-nine patients were recruited (mean age, 50 years; 32 men and 27 women; mean length of diagnosis, 22 years). Individuals were randomly assigned to receive ED intervention or standard control writing intervention. Disease severity, quality of life, and mood were assessed at baseline and at 2, 8, and 12 weeks postintervention.

RESULTS

Disease severity and quality of life improved in both groups over the follow-up period. Preliminary analysis suggested no differences in the magnitude of improvement between the groups. However, predictors of improvement were found to differ. Disease severity on Week 12 was predicted by changes in mood in intervention patients and seasonal variation in control patients. In contrast, quality of life on Week 12 was predicted by baseline quality of life in intervention patients, while seasonal variation approached significance for control patients.

CONCLUSIONS

Changes in mood following ED predicted improvements in disease severity in patients with psoriasis. However, the degree of improvement did not differ between intervention and control patients.

摘要

目的

本研究探讨了情感表露(ED)干预对银屑病患者疾病严重程度和生活质量的影响。

方法

招募了59名患者(平均年龄50岁;男性32名,女性27名;平均诊断时长22年)。将个体随机分配接受ED干预或标准对照写作干预。在基线以及干预后2周、8周和12周评估疾病严重程度、生活质量和情绪。

结果

在随访期间,两组的疾病严重程度和生活质量均有所改善。初步分析表明两组改善程度无差异。然而,发现改善的预测因素有所不同。干预组患者第12周的疾病严重程度可由情绪变化预测,而对照组患者则由季节变化预测。相比之下,干预组患者第12周的生活质量可由基线生活质量预测,而对照组患者季节变化接近显著水平。

结论

ED后情绪变化可预测银屑病患者疾病严重程度的改善。然而,干预组和对照组患者的改善程度无差异。

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