Anpalahan M, Gibson S J
Western Hospital, Melbourne, Victoria, Australia.
Intern Med J. 2008 Jan;38(1):16-23. doi: 10.1111/j.1445-5994.2007.01398.x. Epub 2007 Jun 2.
The aim of this study was to determine the association between the common geriatric syndromes and predefined adverse outcomes of hospitalization and to identify the most important independent predictors of adverse outcomes using information gained within 24 h of admission in older general medical patients.
A prospective longitudinal cohort study of patients aged > or =75 years admitted to the rapid assessment medical unit in a teaching hospital was carried out. The role of geriatric syndromes in predicting outcomes was examined in univariate and multivariate models. The outcome measures were (i) length of hospital stay (LOS) of 28 days or more, (ii) institutionalization or change in residential care status to a more dependent category at discharge or during 3 months post-discharge, (iii) unplanned readmissions during 3 months and (iv) mortality in hospital or 3 months post-discharge.
The presence of geriatric syndromes was significantly associated with increased LOS and institutionalization or change in residential care status to a more dependent category. The factors most predictive of these outcomes were impaired pre-admission functional status in activities of daily living, recurrent falls, urinary incontinence and supported living arrangements. The geriatric syndromes appeared less important in predicting unplanned readmission and death.
The presence of geriatric syndromes in older general medical patients is an important determinant of adverse outcomes of hospitalization, particularly of LOS and admission to residential care. The predictors most useful for screening patients for these outcomes, within 24 h of admission, appear to be the presence of certain pre-existing geriatric syndromes before admission.
本研究旨在确定常见老年综合征与预先定义的住院不良结局之间的关联,并利用老年普通内科患者入院24小时内获取的信息,确定不良结局最重要的独立预测因素。
对一家教学医院快速评估内科病房收治的年龄≥75岁的患者进行了一项前瞻性纵向队列研究。在单变量和多变量模型中检验老年综合征在预测结局中的作用。结局指标包括:(i)住院时间(LOS)达28天或更长;(ii)出院时或出院后3个月内入住机构或居住护理状态转变为更依赖的类别;(iii)3个月内非计划再入院;(iv)住院期间或出院后3个月内死亡。
老年综合征的存在与住院时间延长、入住机构或居住护理状态转变为更依赖的类别显著相关。对这些结局预测性最强的因素是入院前日常生活活动功能状态受损、反复跌倒、尿失禁和支持性生活安排。老年综合征在预测非计划再入院和死亡方面似乎不太重要。
老年普通内科患者中存在老年综合征是住院不良结局的重要决定因素,尤其是住院时间和入住机构护理。入院24小时内,对筛查这些结局最有用的预测因素似乎是入院前存在某些老年综合征。