Tran Luc Viet, Nguyen Thanh Xuan, Nguyen Thu Thi Hoai, Nguyen Huong Thi Thu, Nguyen Tam Ngoc, Nguyen Anh Lan, Naganathan Vasikaran, Thillainadesan Janani, Nguyen Huong Thi Thanh, Nguyen Anh Trung, Vu Huyen Thi Thanh
Scientific Research Department, National Geriatric Hospital, Hanoi, Vietnam.
Neurology Department, Hanoi Medical University, Hanoi, Vietnam.
Dement Geriatr Cogn Dis Extra. 2024 Sep 2;14(1):89-95. doi: 10.1159/000541237. eCollection 2024 Jan-Dec.
The identification of geriatric syndromes in people with dementia is important. The aim of the study was to assess the prevalence of geriatric syndromes among dementia outpatients.
A cross-sectional study was conducted enrolling outpatients with dementia aged ≥60 years old. Dementia was diagnosed by neuropsychiatrists following DSM-5 criteria. The geriatric syndromes assessed included nutritional status (Mini Nutritional Assessment Scale-Short Form), polypharmacy, comorbidities, alcohol use, depression (quality of life in Alzheimer disease), functional status (Barthel Index, Instrumental Activities of Daily Living); lower body strength (30 s stand chair test), and frailty (Timed Up and Go test ≥14 s).
A total of 87 participants was recruited in the study (mean age: 76.8 ± 1.2 years; female: 65.5%). The median number of geriatric syndromes per participant was 5 (IQR = 2); all participants had two or more geriatric syndromes. The most common geriatric syndromes were loss of independence (96.6% impairment in >1 IADL task score and 74.7% dependency in physical function at based on Barthel Index), reduced lower body strength (86.2%), malnutrition and risk of malnutrition (78.2%), and frailty (67.8%). Current and history of smoking, drinking alcohol, using memantine therapy, malnourishment and risk of malnourishment were significantly associated with increasing severity of dementia.
The presence and coincidence of geriatric syndromes is common among outpatients with dementia. These findings have important clinical implications in terms of the assessment and service delivery for older adults in Vietnam. We are exploring ways to enhance our services to provide comprehensive, multidisciplinary approaches to screening, recognition, and treatment of geriatric syndromes in older adults with dementia.
识别痴呆患者中的老年综合征很重要。本研究的目的是评估痴呆门诊患者中老年综合征的患病率。
开展一项横断面研究，纳入年龄≥60岁的痴呆门诊患者。痴呆由神经精神科医生按照《精神疾病诊断与统计手册》第5版标准进行诊断。评估的老年综合征包括营养状况（微型营养评定量表简表）、多重用药、合并症、饮酒情况、抑郁（阿尔茨海默病生活质量）、功能状态（巴氏指数、日常生活活动能力量表）；下肢力量（30秒坐立试验）和衰弱（计时起立行走试验≥14秒）。
本研究共招募了87名参与者（平均年龄：76.8±1.2岁；女性：65.5%）。每位参与者老年综合征的中位数为5种（四分位间距=2）；所有参与者都有两种或更多种老年综合征。最常见的老年综合征是独立性丧失（在>1项日常生活活动能力量表任务得分中96.6%有受损，基于巴氏指数74.7%身体功能存在依赖）、下肢力量下降（86.2%）、营养不良和营养不良风险（78.2%）以及衰弱（67.8%）。当前吸烟史、饮酒史、使用美金刚治疗、营养不良和营养不良风险与痴呆严重程度增加显著相关。
老年综合征在痴呆门诊患者中很常见且同时存在。这些发现对越南老年人的评估和服务提供具有重要的临床意义。我们正在探索改进服务的方法，以提供全面、多学科的方法来筛查、识别和治疗痴呆老年人的老年综合征。
