Vik Peter W
Department of Psychology, Idaho State University, Pocatello, ID 83209-8112, USA.
Womens Health Issues. 2007 Jul-Aug;17(4):256-63. doi: 10.1016/j.whi.2006.12.004. Epub 2007 Jun 4.
Methamphetamine's (MA) impact on psychiatric functioning is not well understood, especially among women. Efforts to understand MA's impact are complicated by the use of other drugs. The purpose of this study is to untangle the relative contributions of MA versus other drugs on psychiatric symptoms.
Incarcerated women (N = 100) completed diagnostic interviews and a symptom measure to establish psychiatric status.
Nearly all women (83%) had lifetime dependence on > or =1 drugs. The most common drug of dependence was MA (67%), followed by alcohol (32%), cannabis (19%), and cocaine (15%). Over half met lifetime criteria for an affective disorder (53%), and nearly half (46%) met lifetime criteria for an anxiety disorder. Lifetime dependence on MA and a nonstimulant drug was related to current psychiatric symptoms and lifetime mood and anxiety disorder. Lifetime mood and anxiety disorders were generally unrelated to recent MA use.
Findings highlight the impact of MA use on psychiatric presentation among women. Results suggest that MA impacts psychiatric symptoms independent of lifetime psychiatric diagnoses. Of note was the high incidence of drug dependence and mood and anxiety disorders among this sample of incarcerated women from a rural state. Findings imply important treatment implications for women in prison settings.
甲基苯丙胺（MA）对精神功能的影响尚未得到充分了解，尤其是在女性中。由于同时使用其他药物，了解MA影响的工作变得复杂。本研究的目的是理清MA与其他药物对精神症状的相对影响。
被监禁的女性（N = 100）完成了诊断访谈和症状测量，以确定精神状态。
几乎所有女性（83%）终生依赖一种或多种药物。最常见的依赖药物是MA（67%），其次是酒精（32%）、大麻（19%）和可卡因（15%）。超过一半的人符合情感障碍的终生标准（53%），近一半（46%）符合焦虑障碍的终生标准。终生对MA和非兴奋剂药物的依赖与当前的精神症状以及终生的情绪和焦虑障碍有关。终生的情绪和焦虑障碍通常与近期使用MA无关。
研究结果突出了使用MA对女性精神表现的影响。结果表明，MA对精神症状的影响独立于终生精神诊断。值得注意的是，来自农村州的这一样本被监禁女性中药物依赖以及情绪和焦虑障碍的发生率很高。研究结果对监狱环境中的女性具有重要的治疗意义。
