Batian A N, Abramovskaia A K, Batian O N
Probl Tuberk. 1991(7):60-2.
Data are given related to a combined examination of 168 pulmonary tuberculosis patients in whom immunomodulating T-activin and levamisole chemotherapy was carried out in 40 subjects. In tuberculosis patients with significantly abnormal parameters of the immunity T-system, side effects of the antituberculosis drugs developed in 67.7%, while in those who were subjected to a general scheme of treatment with inclusion of the immunomodulating drugs in only 17.5%. T-activin was found to be highly effective in preventing side effects of the antituberculosis drugs. A diverse influence of the immunity modulating drugs on some T-lymphocyte classes was registered, which is essential in choosing the suitable modulator and regimen of its use.
给出了对168例肺结核患者进行联合检查的数据，其中40例患者接受了免疫调节T-激活素和左旋咪唑化疗。在免疫T系统参数明显异常的肺结核患者中，67.7%出现了抗结核药物的副作用，而在接受包含免疫调节药物的常规治疗方案的患者中，这一比例仅为17.5%。发现T-激活素在预防抗结核药物的副作用方面非常有效。记录了免疫调节药物对某些T淋巴细胞类别的不同影响，这对于选择合适的调节剂及其使用方案至关重要。
