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医源性损伤后胆管重建新技术的提议:犬类研究及文献综述

Proposal of a new technique for bile duct reconstruction after iatrogenic injury: study in dogs and review of the literature.

作者信息

Crema Eduardo, Trentini Eliane Anrain, Llanos Juan Carlos

机构信息

Experimental Laboratory of Surgery Techniques, Department of Surgery, Federal University of Triângulo Mineiro (UFTM), Minas Gerais, Brazil.

出版信息

Acta Cir Bras. 2007 May-Jun;22(3):162-7. doi: 10.1590/s0102-86502007000300002.

DOI:10.1590/s0102-86502007000300002
PMID:17546287
Abstract

PURPOSE

Interposition of a jejunal tube between the common bile duct and duodenum.

METHODS

Five adult mongrel dogs of both sexes, weighing on average 22.3 kg (18 to 26.5 kg), were used. Obstructive jaundice was induced by ligation of the distal common bile duct. After one week, a 2.5-cm long jejunal tube was fabricated from a segment of the loop removed 15 cm from the Treitz angle and interposed between the common bile duct and duodenum.

RESULTS

The animals presented good clinical evolution and no complications were observed. After 6 weeks, complete integration was noted between the bile duct mucosa, tube and duodenum and a significant reduction in total bilirubin and alkaline phosphatase was observed when compared to the values obtained one week after ligation of the common bile duct.

CONCLUSION

The jejunal tube interposed between the dilated bile duct and duodenum showed good anatomic integration and reduced total bilirubin and alkaline phosphatase levels in the animals studied.

摘要

目的

在胆总管和十二指肠之间置入空肠管。

方法

使用5只成年杂种犬,雌雄不限,平均体重22.3千克(18至26.5千克)。通过结扎胆总管远端诱导梗阻性黄疸。一周后,从距Treitz韧带15厘米处切除的一段肠袢制作一根2.5厘米长的空肠管,并将其置于胆总管和十二指肠之间。

结果

动物临床进展良好,未观察到并发症。6周后,观察到胆管黏膜、空肠管和十二指肠之间完全融合,与胆总管结扎一周后测得的值相比,总胆红素和碱性磷酸酶显著降低。

结论

在扩张的胆管和十二指肠之间置入的空肠管在研究的动物中显示出良好的解剖融合,并降低了总胆红素和碱性磷酸酶水平。

相似文献

1
Proposal of a new technique for bile duct reconstruction after iatrogenic injury: study in dogs and review of the literature.医源性损伤后胆管重建新技术的提议:犬类研究及文献综述
Acta Cir Bras. 2007 May-Jun;22(3):162-7. doi: 10.1590/s0102-86502007000300002.
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[Late stage stenoses of bile ducts after iatrogenic bile duct injuries following cholecystectomy].[胆囊切除术后医源性胆管损伤所致晚期胆管狭窄]
Zentralbl Chir. 2007 Dec;132(6):523-8. doi: 10.1055/s-2007-981372.
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[Long-term follow up of bile duct injury by laparoscopic cholecystectomy and reconstruction with jejunum interposition].腹腔镜胆囊切除术后胆管损伤并空肠间置重建的长期随访
Chirurg. 2000 Dec;71(12):1500-3. doi: 10.1007/s001040051251.
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Bile duct injury during laparoscopic cholecystectomy.腹腔镜胆囊切除术期间的胆管损伤。
Can J Surg. 1993 Dec;36(6):509-16.
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[Treatment of common bile duct lesions].
Langenbecks Arch Chir. 1972;331(2):87-107. doi: 10.1007/BF01263249.
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Postoperative anastomotic bile duct stricture is affected by the experience of surgeons and the choice of surgical procedures but not the timing of repair after obstructive bile duct injury.术后吻合口胆管狭窄受外科医生经验和手术方式选择的影响,但不受胆管损伤后修复时机的影响。
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Endoluminal reconstruction of the canine common biliary duct.犬胆总管的腔内重建
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A simple animal model for inducing and releasing surgical jaundice in rats.一种用于诱导和解除大鼠外科性黄疸的简单动物模型。
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引用本文的文献

1
Laparoscopic reconstruction of the extrahepatic bile duct using a jejunal tube: an innovative, more physiological and anatomical technique for biliodigestive derivation†.使用空肠管进行腹腔镜下肝外胆管重建:一种用于胆肠吻合的创新、更符合生理和解剖学的技术†
J Surg Case Rep. 2014 Jan 7;2014(1). doi: 10.1093/jscr/rjt106. Print 2014 Jan.