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小型动物麻醉实验装置

Anesthetic experimental device for small animal.

作者信息

Vivas Luiz Alfredo de Magalhães, Jamel Nelson, Refinetti Ricardo Antonio, Silva Luis Felipe da, Rodrigues Lígia Villela, Silva Paulo Cesar, Schanaider Alberto

机构信息

Department of Surgery, FM, UFRJ, Brazil.

出版信息

Acta Cir Bras. 2007 May-Jun;22(3):229-33. doi: 10.1590/s0102-86502007000300012.

DOI:10.1590/s0102-86502007000300012
PMID:17546297
Abstract

PURPOSE

The difficulty to anesthetize small laboratory animals with vaporizer prompted us to go in search of new materials, and create new techniques. The improved equipment of anesthesia we looked for should be low cost, practical, versatile, and its management serve ethical, teaching, and research purposes.

METHODS

The new components of the equipment were: the vaporizer, the unidirectional valve, the glass cylinder filled with water, the flow guidance y-shape tube, the flow regulators, the mask modifications, and another free airway for emergency occurrence. A test was done with 30 Wistar rats, Rattus norvegicus albinus, divided into three groups with 10 rats for each one. Groups 1, 2 and 3 were anesthetized with Ether, Halothane and Sevoflurane respectively, using the new gadget. The anesthetic induction time, the breathing rhythm alteration during an anesthesia pre-established time (10 minutes), and the recovery time were observed.

RESULTS

The equipment enabled an easy handling, and fulfilled a larger safeness and stability during the induction and anesthetic management. The test showed it was possible to make use of several anesthetic agents.

CONCLUSION

The device is effective, and turns the anesthesia procedure into a very easy practice with low-cost. It should be recommended for experimental surgery, teaching and research.

摘要

目的

用蒸发器麻醉小型实验动物存在困难,这促使我们寻找新材料并创造新技术。我们所寻求的改进型麻醉设备应成本低廉、实用、多功能,且其操作应服务于伦理、教学和研究目的。

方法

该设备的新组件包括:蒸发器、单向阀、装有水的玻璃圆筒、导流Y形管、流量调节器、面罩改进装置以及另一个用于紧急情况的气道。对30只Wistar大鼠(白化挪威大鼠)进行了测试,将其分为三组,每组10只。分别使用新装置用乙醚、氟烷和七氟醚对第1、2和3组进行麻醉。观察麻醉诱导时间、在预先设定的麻醉时间(10分钟)内呼吸节律的改变以及恢复时间。

结果

该设备操作简便,在诱导和麻醉管理过程中具有更高的安全性和稳定性。测试表明可以使用多种麻醉剂。

结论

该装置有效,使麻醉过程成为一种低成本且非常简便的操作。推荐用于实验手术、教学和研究。

相似文献

1
Anesthetic experimental device for small animal.小型动物麻醉实验装置
Acta Cir Bras. 2007 May-Jun;22(3):229-33. doi: 10.1590/s0102-86502007000300012.
2
Inhalation anesthesia equipment for rats with provision of simultaneous anesthetic and oxygen.用于大鼠的吸入麻醉设备,可同时提供麻醉剂和氧气。
Acta Cir Bras. 2011 Apr;26(2):140-3. doi: 10.1590/s0102-86502011000200012.
3
Usefulness of an anesthetic conserving device (AnaConDa™) in sevoflurane anesthesia.麻醉节省装置(AnaConDa™)在七氟醚麻醉中的作用。
Minerva Anestesiol. 2012 Mar;78(3):310-4.
4
Accuracy of isoflurane, halothane, and sevoflurane vaporizers during high oxygen flow and at maximum vaporizer dial setting.异氟烷、氟烷和七氟烷蒸发器在高氧流量及蒸发器刻度盘最大设定值时的准确性。
Am J Vet Res. 2011 Jun;72(6):751-6. doi: 10.2460/ajvr.72.6.751.
5
An inhaler device using liquid injection of isoflurane for short term anesthesia in piglets.一种用于仔猪短期麻醉的采用异氟烷液体注射的吸入器装置。
Vet Anaesth Analg. 2006 Jul;33(4):207-13. doi: 10.1111/j.1467-2995.2005.00258.x.
6
Comparison of anesthetic induction in cats by use of isoflurane in an anesthetic chamber with a conventional vapor or liquid injection technique.在麻醉箱中使用异氟烷通过传统蒸汽或液体注射技术对猫进行麻醉诱导的比较。
J Am Vet Med Assoc. 2008 Jul 15;233(2):262-6. doi: 10.2460/javma.233.2.262.
7
Comparison of isoflurane with sevoflurane for anesthesia induction and recovery in adult dogs.异氟烷与七氟烷用于成年犬麻醉诱导和苏醒的比较。
Am J Vet Res. 1998 Apr;59(4):478-81.
8
A closed anesthetic system for small laboratory animals.
Lab Anim Sci. 1984 Feb;34(1):77-8.
9
An apparatus for anesthetizing small laboratory animals.
Lab Anim Sci. 1975 Aug;25(4):481-2.
10
Assessment of halothane and sevoflurane anesthesia in spontaneously breathing rats.自主呼吸大鼠中氟烷和七氟烷麻醉的评估。
Am J Vet Res. 2003 Apr;64(4):470-4. doi: 10.2460/ajvr.2003.64.470.

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