Young G A R, Iland H J
Institute of Haematology, Royal Prince Alfred Hospital and Department of Medicine, University of Sydney, Sydney, New South Wales, Australia.
Intern Med J. 2007 Jul;37(7):478-84. doi: 10.1111/j.1445-5994.2007.01402.x.
The classification of both Hodgkin's and non-Hodgkin's lymphomas continues to evolve. The current World Health Organization classification incorporates data derived from advances in our understanding of the pathogenesis of these disorders together with their distinguishing immunophenotypic, genotypic, clinical and histopathological characteristics. As outcomes have improved, the main emphasis of treatment has been to incorporate a risk-adapted approach to reduce long-term toxicity without sacrificing efficacy through the use of varying combinations of chemotherapy, radiotherapy and immunotherapy.
霍奇金淋巴瘤和非霍奇金淋巴瘤的分类都在不断发展。世界卫生组织目前的分类纳入了源自我们对这些疾病发病机制理解的进展的数据，以及它们独特的免疫表型、基因型、临床和组织病理学特征。随着治疗效果的改善，治疗的主要重点是采用风险适应性方法，通过使用化疗、放疗和免疫疗法的不同组合，在不牺牲疗效的情况下降低长期毒性。
