Polito P, Perin T, Cilia A, Carbone A
Divisione di Anatomia Patologica, Instituto di Ricovero e Cura a Carattere Scientifico, Aviano.
Pathologica. 1994 Aug;86(4):337-49.
Cytogenetic analysis of Non-Hodgkin's Lymphomas (NHL) taken together with immunophenotypic and genotypic studies, may contribute to better define their morphologic classification. In this review the main cytogenetic data have been summarized, looking at a histopathologic NHL categorization that is related to a modern multiparametric approach. The correlation of non random chromosome abnormalities with NHL categories will augment information about their pathogenesis and tumor progression.
非霍奇金淋巴瘤(NHL)的细胞遗传学分析,结合免疫表型和基因分型研究,可能有助于更好地界定其形态学分类。在这篇综述中,主要的细胞遗传学数据已被总结,着眼于与现代多参数方法相关的组织病理学NHL分类。非随机性染色体异常与NHL类别之间的相关性将增加有关其发病机制和肿瘤进展的信息。