Plasmapheresis for chronic inflammatory demyelinating polyradiculoneuropathy.

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated disorder characterized by progressive or relapsing symmetrical motor or sensory symptoms and signs in more than one limb, developing over at least 2 months. It may cause prolonged periods of disability and even death. Evidence from trials suggests that plasma exchange provides significant short-term benefit in about two thirds of patients with chronic inflammatory demyelinating polyradiculoneuropathy. This review evaluates the role of plasmapheresis in CIDP.