Strohschein Lisa A
Department of Sociology, University of Alberta, Edmonton, Alta.
CMAJ. 2007 Jun 5;176(12):1711-4. doi: 10.1503/cmaj.061458.
Evidence suggests that children living in single-parent or step-parent households are more likely than children in households with 2 biological parents to be prescribed methylphenidate. I conducted a study of prospective data to investigate parental divorce as a predictor of methylphenidate use.
I used data for children who participated in the National Longitudinal Survey of Children and Youth from 1994 to 2000. The sample was restricted to children who remained in the survey in 2000 and who, at initial interview, lived in a household with 2 biological parents (n = 4784). A generalized estimating equation model was used to compare the odds ratios of methylphenidate use among children whose parents obtained a divorce between 1994 and 2000 relative to children whose parents remained married during this period.
Between 1994 and 2000, 633 children (13.2%) experienced the divorce of their parents. The proportion of children who received methylphenidate at any time between 1994 and 2000 was 3.3% among those whose parents remained married and 6.1% among those whose parents divorced during this period. After adjustment for age of the mother and sex and age of the child, I found that methylphenidate use was significantly higher among children whose parents subsequently divorced than among those whose parents remained married (odds ratio 1.82, 95% confidence interval 1.01-3.33).
The increased risk of children receiving a prescription for methylphenidate in the period following parental divorce raises questions about the causal links in this association. Future research is needed to replicate these findings and to investigate possible explanations.
有证据表明,与生活在双亲家庭的孩子相比,单亲家庭或继亲家庭的孩子更有可能被开具哌甲酯处方。我进行了一项前瞻性数据研究,以调查父母离婚作为哌甲酯使用的预测因素。
我使用了1994年至2000年参加全国儿童和青少年纵向调查的儿童数据。样本仅限于2000年仍参与调查且在初次访谈时生活在双亲家庭的儿童(n = 4784)。使用广义估计方程模型比较1994年至2000年父母离婚的儿童与父母在此期间保持婚姻关系的儿童使用哌甲酯的比值比。
1994年至2000年期间,633名儿童(13.2%)经历了父母离婚。1994年至2000年期间,父母保持婚姻关系的儿童中,任何时候接受哌甲酯治疗的比例为3.3%,而在此期间父母离婚的儿童中这一比例为6.1%。在对母亲年龄、孩子性别和年龄进行调整后,我发现父母随后离婚的儿童使用哌甲酯的比例显著高于父母保持婚姻关系的儿童(比值比1.82,95%置信区间1.01 - 3.33)。
父母离婚后儿童获得哌甲酯处方的风险增加,这引发了对这种关联中因果关系的质疑。需要进一步研究来重复这些发现并调查可能的解释。