Horev G, Kornreich L, Hadar H, Katz K
Department of Pediatric Radiology, Beilinson Medical Center, School of Medicine, TA University, Petach-Tikva, Israel.
Skeletal Radiol. 1991;20(7):479-82. doi: 10.1007/BF00194240.
Children suffering from Gaucher's disease were examined by magnetic resonance imaging (MRI) during a characteristic episode of "bone crisis". An unexpectedly high intramedullary as well as subperiosteal signal was observed on both the T1- and T2-weighted sequences in 5 patients, suggesting a subacute hemorrhage or hematoma. It is conceivable that such a painful hemorrhage is an important component of the "bone crisis" phenomenon. Furthermore, in these cases this is a specific sign which may enable differentiation of bone crises from other types of bone pain associated with Gaucher's disease.
在“骨危象”的典型发作期间，对患有戈谢病的儿童进行了磁共振成像（MRI）检查。在5例患者的T1加权和T2加权序列上均观察到意外高的骨髓内及骨膜下信号，提示亚急性出血或血肿。可以想象，这种疼痛性出血是“骨危象”现象的一个重要组成部分。此外，在这些病例中，这是一个特定的征象，可能有助于将骨危象与戈谢病相关的其他类型骨痛区分开来。
