Fugh-Berman Adriane, Bythrow Jenna
Department of Physiology and Biophysics, Georgetown University School of Medicine, 571460, Washington, DC 20052-1460, USA.
J Gen Intern Med. 2007 Jul;22(7):1030-4. doi: 10.1007/s11606-007-0141-4. Epub 2007 Mar 7.
Progesterone creams and natural or bioidentical compounded estrogen preparations are being promoted to consumers as safe alternatives to conventional menopausal hormone therapy and as health-promoting tonics. No reliable data support these claims.
Natural hormones, including estradiol, estriol, estrone, and progesterone, can be expected to have the same adverse event profile as conventional menopausal hormone regimens.
Salivary tests may be used to persuade asymptomatic consumers to use hormones (or symptomatic patients to use higher doses than those needed to mitigate symptoms), a practice that can be expected to result in adverse events.
孕酮乳膏以及天然或生物等效的复合雌激素制剂作为传统绝经激素疗法的安全替代品以及促进健康的滋补品向消费者进行推广。但并无可靠数据支持这些说法。
天然激素，包括雌二醇、雌三醇、雌酮和孕酮，预计会与传统绝经激素疗法有相同的不良事件谱。
唾液检测可能被用于说服无症状的消费者使用激素（或有症状的患者使用高于缓解症状所需剂量的激素），这种做法预计会导致不良事件。
