El-Housseiny Azza A, Saleh Susan M, El-Masry Ashraf A, Allam Amany A
Pediatric and Community Dentistry Department, Faculty of Dentistry, University of Alexandria, El-Ibrahimia, Alexandria, Egypt.
J Clin Pediatr Dent. 2007 Spring;31(3):167-70.
The aim of this study was to study the effect of vitamin "E" in the treatment of oral mucositis. 80 patients with oral mucositis were randomly distributed into 2 groups: group A, topically applied vitamin "E" and group B, vitamin "E" was given systemically. The 2 groups were evaluated for 5 days. Results showed that in group A grades of oral mucositis improved significantly, while in group B no significant improvement was noticed. It is concluded that topical application of 100 mg vitamin "E" twice daily is an effective measure for the treatment of chemotherapy-induced oral mucositis.
本研究的目的是探讨维生素“E”治疗口腔黏膜炎的效果。80例口腔黏膜炎患者被随机分为2组:A组局部应用维生素“E”,B组全身应用维生素“E”。对两组进行了5天的评估。结果显示,A组口腔黏膜炎的分级有显著改善,而B组未观察到明显改善。结论是,每天两次局部应用100毫克维生素“E”是治疗化疗引起的口腔黏膜炎的有效措施。